Ghana defender Daniel Amartey admitted his team were determined that if they could not qualify for the World Cup knockout stage, they would at least prevent Uruguay from doing so.
Giorgian De Arrascaeta netted twice in quick succession in the first half, with 35-year-old Luis Suarez having a hand in both goals
FIFA World Cup 2022: Ghana will be facing their Uruguay in their last Group H match of the FIFA World Cup 2022, at the Al Janoub Stadium on Friday
FIFA World Cup 2022: After a pulsating fortnight of first round action, the World Cup's group stage draws to a close with the final games in Groups G and H
FIFA World Cup 2022, South Korea vs Portugal and Uruguay vs Ghana, Group H Highlights: South Korea stunned Portugal with a late goal, as they defeated the Cristiano Ronaldo-led side 2-1 to enter the Round of 16 stage, on Friday
FIFA World Cup: Uruguay great Luis Suarez refused to apologise on Thursday to Ghanaians over his infamous handball at the World Cup 12 years ago
This time it is Uruguay who are up against it -- a Ghana win would put them into the last 16 and send Uruguay home, but a draw for Ghana could also be enough.
South Korea played their heart out in a Group H match against Ghana before going down 2-3 in a pulsating encounter on Monday.
Mohammed Kudus scored twice as Ghana edged South Korea 3-2 in a dramatic World Cup match on Monday to keep alive their hopes of reaching the last 16.
FIFA World Cup 2022, South Korea vs Ghana Highlights: Mohammed Kudus' brace helped Ghana secure a 3-2 win over South Korea.
Cristiano Ronaldo went down after a tackle by Mohammed Salisu on Thursday before scoring the resulting spot-kick to become the first man to net at five World Cups
Ghana coach Otto Addo insisted Thursday that the spot-kick from which Cristiano Ronaldo's netted in his fifth World Cup was a "gift" following the Black Stars' defeat to Portugal.
Ronaldo became the first man to score at five World Cups on Thursday when he scored the opening goal from the penalty spot in Portugal's 3-2 win over Ghana
Cristiano Ronaldo became the first man to score at five World Cups on Thursday after opening the scoring in Portugal's World Cup clash with Ghana.
FIFA World Cup 2022, Portugal vs Ghana Highlights: Cristiano Ronaldo got on the scoresheet as Portugal edged out Ghana 3-2 in a Group H match at the Stadium 974 on Thursday
Spain winger Nico Williams wants to take his sibling rivalry with older brother, Ghana striker Inaki Williams, from local parks to the biggest stage of all.
The World Cup always provides a stage for young players to make a name for themselves and the younger generation will be eagerly awaiting Sunday's start of the latest edition
Andre Ayew, 32, was part of the Ghana team that came close to becoming the first African side to reach a World Cup semi-final in 2010.