Tottenham have not won an English top-flight title in 60 years, but showed their title credentials with a defensive resilience to frustrate Manchester City's domination of possession.
Youri Tielemans and Dries Mertens scored the goals which gave world number one Belgium victory over Gareth Southgate's England.
England captain Harry Kane is sixth on his country's all-time scoring chart with 32 international goals, 21 behind record-holder Wayne Rooney.
Tottenham have not taken as many risks since that wake-up call, grinding out a 1-0 win at Burnley and a 2-1 victory against Brighton, which was followed by the late victory at West Brom.
Premier League: Harry Kane scored his 150th goal in the league as Tottenham Hotspur beat West Brom 1-0 before Leicester City beat Wolves 1-0.
Harry Kane became the third player to score 200 goals for Tottenham Hotspur, bringing up his double century -- in his 300th appearance for the club.
Harry Kane's speech impediment was mocked by some journalists even as the striker moved into the top 10 scorers in the Premier League.
The 2-1 win over Brighton, lifted Tottenham up to second in the Premier League table.
South Korea forward Son Heung-min scored his eighth league goal of the Premier League season in the 76th minute, heading in from close range after a headed pass from Harry Kane.
Gareth Bale came on as a 72nd minute substitute with Tottenham leading 3-0, but suffered a debut to forget as the North London club capitulated in astonishing fashion.
Tottenham Hotspur manager Jose Mourinho questioned his side's mental strength after a stunning late collapse resulted in a 3-3 draw against West Ham on Sunday.
Harry Kane has been dealing with muscle fatigue and he was not involved in a friendly match against Wales on October 8.
Manchester United got a hiding from Tottenham Hotspur and their skipper Harry Maguire made no friends with his on-field exploits.
Tottenham cashed in on Anthony Martial's first-half red card to thrash Manchester United 6-1 as Jose Mourinho enjoyed a dream return to Old Trafford on Sunday.
Raheem Sterling's last-minute penalty salvaged England from another embarrassing result against Iceland.
England and Tottenham Hotspur striker Harry Kane was highly impressed with Indian skipper Virat Kohli's football technique.
Jan Vertonghen, whose contract was extended in June until the end of the current season, made more than 300 appearances for Spurs after joining the club from Ajax in 2012.
Tottenham took the lead through James Justin's early own goal before Harry Kane took centre stage with two superb finishes before half-time.