Both Madrid sides suffered a familiar lack of cutting edge in front of goal this La Liga season.
Paul Pogba, back after over two months out with a hamstring injury, carved out a superb 37th-minute equaliser for Manchester United.
Jesus and De Bruyne struck either side of half-time at the King Power Stadium as Pep Guardiola's ruthless side registered a 16th successive victory in all competitions.
NorthEast could have got their opening goal as early as in third minute, but Marcinho fluffed a very easy chance when he hit on high after being on a one on one with goalkeeper Subrata Paul.
New outfit Bengaluru FC will make their much-awaited Indian Super League debut when they cross swords with last season's semi-finalists Mumbai City FC.
The two coaches - John Gregory (Chennaiyin FC) and Sergio Lobera (Goa) sounded upbeat about their preparations and said the pre-season had been very good and the players were looking forward to the first game.
If Cristiano Ronaldo wins the upcoming Ballon D'Or, he will tie Lionel Messi on five victories.
Chris Coleman will be given the job of lifting Sunderland off the bottom of the table and ultimately winning promotion back to the Premier League.
The match was a box-to-box affair with very few chances coming in the way of both the sides.
The former India captain posted a message on his official Twitter account.
The winner of the fourth season will get a direct spot in the AFC Cup (Asia's equivalent of Europe's Europa League).
More Indian players, more teams, more matches and more months - this is already being touted an ISL with a difference.
Chennaiyin FC coach John Gregory said the team had a good pre-season ahead of the fourth season of Indian Super League.
Jefferson Farfan and Christian Ramos scored as Peru defeated New Zealand to reach the World Cup for the first time since 1982 on Wednesday, sealing the last ticket to Russia with a 2-0 win.
Ventura had defended his leadership as "one of the best records in 40 years" despite failing to lead the 1934, 1938, 1982 and 2006 winners to their 19th World Cup.
Indian fans have been used to seeing the likes of Italy's Alessandro Del Piero and Argentine Diego Forlan during the ISL's first three seasons.
Eriksen's magnificent hat-trick inspired Denmark to a 5-1 demolition of the Republic of Ireland.
Already through to the main tournament, India played out a 2-2 draw against Myanmar in the return-leg match of the AFC Asian Cup qualifying Group A match on Tuesday.