Italy's fourth win in five games leaves Gian Piero Ventura's men second in Group G, on the same points as leaders Spain, who beat Israel 4-1.
Messi stroked home his penalty on 16 minutes after veteran Chile defender Jose Fuenzalida brought down Angel Di Maria with a clumsy challenge.
It was only fitting that the Galatasaray forward, who joins Japan's Vissel Kobe next season, should claim his 49th goal on his 130th -- and final -- international appearance.
The last time India emerged victorious in an away international friendly was way back in 2006, when the team captained by Shanmugam Venkatesh eked out a solitary goal win over Pakistan.
Wenger said last week he has reached a decision on whether he will stay at the Premier League club beyond this season, and will announce it publicly "very soon."
Bastian Schweinsteiger, a key member of Germany's 2014 World Cup-winning team, heads to the United States after an unhappy stint with Manchester United.
Oliver, the same referee who was surrounded by Manchester United players in the fractious FA Cup quarter-final with Chelsea last week and resulted in the club being fined £20,000 (23,000 euros, $24,700), awarded a penalty to Liverpool when he judged Gael Clichy to have fouled Roberto Firmino in the 50th minute.
Arsenal's support is split over Arsene Wenger, who won seven trophies in his first nine seasons as manager but has won only two FA Cups in the 12 years since.
While Barcelona defeated Valencia 4-2 in the La Liga on Sunday, Atletico Madrid beat Sevilla 3-1.
Marouane Fellaini finally repaid manager Jose Mourinho's faith by scoring his first Premier League goal in 15 months. Manchester United moved up to fifth as they extended their unbeaten run in the league to 18 games.
Chelsea provisionally opened a 13-point gap at the top of the table thanks to their 2-1 win over Stoke City while Arsenal suffered their fourth loss in five Premier League games.
Craig Dawson scored twice as West Brom condemned Arsenal to a fourth defeat in five league games, which left them five points off the Champions League places.
Chelsea defeated Manchester United 1-0 to enter the semi-finals of the FA Cup and knock the defending champions out.
The Europa League quarterfinal clash will be the fourth meeting between Manchester United and Anderlecht, with the English club winning the three previous ones.
Colombia are the favourites to take the fourth slot as they need just a point on the final match day on Sunday to finish ahead of Ecuador and Venezuela.
The Champions League quarterfinal fixtures were announced on Friday after the draw at UEFA headquarters in Nyon, Switzerland.
Juan Mata struck 20 minutes from the end of a subdued game, completing a 2-1 aggregate win that sent United into the last eight of Europe's second-tier club competition for the first time since 1985.
Trailing 5-3 from the first leg in England, first-half strikes from teenage sensation Kylian Mbappe and Fabinho put the home side in control of the return clash at the Stade Louis II.