Harry Kane is Tottenham's top scorer this season with 20 goals in 31 appearances in all competitions.
David De Gea produced a masterclass on Sunday to protect Manchester United's 1-0 lead against Tottenham.
Fourth-placed Chelsea have won five of their last seven league matches and sit six points clear of fifth-placed Arsenal.
Saturday's early kick-off saw teenage midfielder Declan Rice score his first West Ham goal in a 1-0 win at home to London rivals Arsenal.
Chelsea will only receive payments related to Cesc Fabregas' performance on the Mediterranean coast.
Chelsea have reportedly turned down a 35 million pounds (USD 45 million) bid from Bayern Munich for the 18-year-old.
Aaron Ramsey is already free to sign a pre-contract agreement with foreign clubs.
Jose Mourinho's time at Real between 2010-2013 brought a league title and a Spanish Cup.
Gonzalo Higuain joined Milan on a season-long loan from Juventus with an option to buy but has struggled to settle at the San Siro.
Alex Ferguson has guided Manchester United to numerous trophies including two Champions League titles during his 27-year reign.
Manchester United have won all five matches since Ole Gunnar Solskjaer took the helm at Old Trafford following the sacking of Jose Mourinho.
Naby Keita has made 18 appearances so far this season but he has failed to feature in the past three matches for Liverpool.
Manchester City recently suffered back-to-back defeats against Crystal Palace and Leicester City.
Chelsea remain in fourth place, but they are now just three points ahead of fifth placed Arsenal in the race to qualify for next season's Champions League.
Romelu Lukaku and Marcus Rashford were the goal scorers for Manchester United.
In November 2018, Christian Pulisic became the youngest player to captain the United States senior side aged 20 years and 63 days.
Harry Kane's third-minute opening goal is the fifth successive New Year's Day he has scored in the Premier League, equalling a record held by Andy Cole and Steven Gerrard.