Sri Lanka Cricket Secretary Mohan de Silva said they received the all-clear from the defence ministry to leave for Pakistan on Tuesday.
Misbah-ul-Haq recently took up his new assignment as Head Coach and Chief Selector of the Pakistan men's cricket team and has issued a directive for a strict diet plan, say reports.
Both Ahmed Shehzad and Umar Akmal have been out of favour with the previous national selection committee and the team management and were not considered for the World Cup earlier this year.
Wasim Akram said the entire country needed to be smacked on the face for failing to give their star boxer Muhammad Waseem a hero's welcome.
Javed Miandad urged all the Pakistani players to concentrate on putting up their best foot forward in the series.
PCB Chairman Ehsan Mani is hopeful that the trio of Misbah-ul-Haq, Sarfaraz Ahmed and Babar Azam will do well for Pakistan.
Sri Lanka are scheduled to play three ODIS and as many T20Is in Karachi and Lahore between September 27 and October 9.
Some senior Sri Lankan players have pulled out of the tour of Pakistan because of security concerns.
The board said the Sri Lankan Prime Minister's Office had advised it to "reassess the situation" after it received "reliable information of a possible terrorist threat" against the national squad.
Lahiru Thirimanne will lead the 15-member ODI squad, while the 16-member T20I squad will be led by Dasun Shanaka.
Sri Lanka's Sports Minister Harin Fernando has rejected claims made by Pakistan Minister Fawad Chaudhry that India forced the players of the island nation to opt out of their upcoming tour against Pakistan.
Science and Technology Minister Fawad Hussain Chaudhry said India threatened the players from Sri Lanka against participating in the upcoming series in Pakistan.
Sri Lanka are scheduled to play three ODIs and as many T20Is, starting from September 27 to October 9.
Spin legend Abdul Qadir died in Lahore on Friday after suffering a cardiac arrest.
Abdul Qadir was 63 years old and is survived by his wife, four sons and a daughter who is married to current Pakistan star batsman Umar Akmal.
Shoaib Akhtar took a humorous dig at Misbah-ul-Haq, a day after the latter was appointed as the head coach and chief selector of Pakistan cricket team.
The Pakistan Cricket Board has appointed Misbah-ul-Haq and Waqar Younis for terms of three years each.
The PCB had advertised for the head coach's position on August 9 and Monday was the last date to apply for the post.