The Windies ran riot in the opening match of a triangular series also featuring Bangladesh.
John Campbell and Shai Hope exceeded the previous best opening partnership of 304 set by Pakistan's Imam-ul-Haq and Fakhar Zaman.
Ben Foakes stumping of Ireland's Andy Balbirnie has left the cricketing world divided with some even claiming that it was worse than 'mankading'.
England collapsed to 66 for five chasing a modest 199 for victory before Ben Foakes along with Tom Curran came to the rescue.
Afghanistan needed only 118 runs to complete formalities against Ireland on Day 4.
Tim Murtagh scored 54 not out and 27 in each innings for Ireland vs Afghanistan to create a new Test record.
Chasing 147 to win, Afghanistan were 29 for one at stumps on Day 3.
Ireland trail by 120 runs with eight wickets in hand after the team's battling line-up crumbed against the Afghan spin attack on day one.
Ireland number 11 Tim Murtagh made an unbeaten 54 to lift Ireland to 172
Ireland depended on a 81-run second-wicket stand between Paul Stirling and Andy Balbirnie to achieve their target as the series ended at 2-2.
Aftab Alam claimed four wickets as Afghanistan dismissed Ireland for 114, 109 runs short of the target.
Andy Balbirnie hit eight sixes and eight fours to set up the morale-boosting win that levelled the five match one-day series 1-1.
Afghanistan posted 250 for seven in 48.3 overs before rain curtailed their innings and no further play was possible in Dehradun.
Gulbadin Naib took two wickets and struck a crucial 46 as Afghanistan outplayed Ireland by five wickets to take a 1-0 lead in the five-ODI series.
Highlights: AFG Vs IRE 1st ODI: Afghanistan registered a 3-0 clean sweep against Ireland in the three-match T20I series.
Rashid Khan claimed a hat-trick to power Afghanistan to a 3-0 series sweep over Ireland.
Afghanistan broke a few records in the second T20 International against Ireland in Dehradun on Saturday.
Live Cricket Score: AFG Vs IRE 2nd T20I: Afghanistan lead the three-match series 1-0.