Ousmane Dembele has never been a deadly finisher and was guilty of missing a couple of big chances in the first half.
A third-minute goal from Jadon Sancho and Marco Reus' late strike sent Borussia Dortmund through to the Champions League last eight.
PSV Eindhoven coach Peter Bosz was left ruing missed chances after his side squandered several opportunities in a 1-1 draw with Borussia Dortmund in the Champions League.
Holders Manchester City and RB Leipzig became the first teams to reach the last 16 of this season's Champions League on Tuesday.
All football matches in England and Scotland were postponed over the weekend following the death of Queen Elizabeth II on Thursday.
Manchester United were placed in the same section as Real Sociedad in Friday's draw for this season's UEFA Europa League in Istanbul, while Arsenal will come up against PSV Eindhoven
Former Dutch international and PSV Eindhoven midfielder Davy Propper on Tuesday announced his retirement from professional football, citing lack of motivation and isolation because of the coronavirus pandemic.
Benfica captain Nicolas Otamendi said reaching the Champions League group stage was an "objective" after the two-time winners held onto a goalless draw in Tuesday's second-leg at Eindhoven
Mario Goetze, who was a free agent after Borussia Dortmund allowed him to leave, has signed a contract with Dutch club PSV Eindhoven.
Tottenham only had to match Inter Milan's result at home to PSV Eindhoven, which they did, as the Italians only managed a 1-1 draw themselves.
Tottenham Hotspur have just one point after three matches in Group B.
Lionel Messi scored a hat-trick as Barcelona put four goals past PSV Eindhoven in the Champions League.
Atletico Madrid defeated PSV Eindhoven 8-7 on penalties in Champions League last 16 games, after both sides could not score in two legs of the match
Manchester United F.C. full-back Luke Shaw suffered a double fracture on his right leg as the Red Devils made their Champions League return with a 2-1 loss against PSV Eindhoven.
Memphis Depay, the 21-year-old Holland forward, agreed to join United from Dutch champions PSV Eindhoven last week in a deal reportedly worth around £25 million ($38 million, 33.6 million euros).
Milan coach Massimilano Allegri, who was lucky to hang on to his job at the end of last season as the Rossoneri finished third following a disastrous first half of the campaign, said his joy was tempered by renewed criticism.
Meanwhile, seven-time winners AC Milan face Dutch runners-up PSV Eindhoven -- a rematch of the 2004-05 semi-final which the Italians won on away goals -- while French side Lyon will play Real Socieded of Spain.
Park played for PSV in 2003-2005 under Guus Hiddink, a former South Korea coach. Park then moved to Manchester United, where he won the 2008 Champions League and four Premier League titles.