With two draws on the road, LaLiga defending champions Real Madrid find themselves seven points behind current league leaders Barcelona with a game in hand.
UEFA Champions League winners Real Madrid lost 1-0 to AC Milan in pre-season, thanks to a goal by Samu Chukwueze.
Barcelona were thrashed in the Spanish Super Cup on Sunday in Saudi Arabia, leading to a week of soul searching ahead of the trip to Seville
Lucas Vazquez headed home to lift Madrid above Girona to the number one spot after this season's surprise packages were held to a 1-1 draw at Real Betis earlier in the day
West Ham's 17-match unbeaten European run came to an end on Thursday with a 2-1 loss away to Olympiakos.
The emphatic victory places Barcelona provisionally top of the table, a point clear of rivals Real Madrid who host Real Sociedad on Sunday.
Pedri and Ferran Torres' late strikes earned La Liga champions Barcelona a 2-0 win over Cadiz in their first competitive home game away from Camp Nou on Sunday.
Real Betis players Aitor Ruibal and Borja Iglesias strongly criticised homophobic attacks from social media users late Sunday after being pictured holding bags at a wedding during the weekend
Andreas Christensen, Robert Lewandowski and Raphinha struck for Barca at Camp Nou with Guido Rodriguez netting a late own goal to round off the rout.
Girona striker Taty Castellanos hit an incredible four goals as his side thrashed champions Real Madrid 4-2 in La Liga on Tuesday, helping leaders Barcelona edge closer to the trophy
Manchester United bounced back from a historic thrashing by Liverpool to beat Real Betis 4-1 in the first leg of their Europa League last 16 tie on Thursday, while a 2-2 draw away to Sporting Lisbon gave Arsenal work to do to reach the quarter-finals
Barcelona clung on with 10 men to beat Valencia 1-0 and move nine points clear of Real Madrid at the top of La Liga on Sunday, thanks to Raphinha's early header
Raphinha put Barcelona ahead in the 65th minute and Robert Lewandowski, back after a three-match league ban, netted the second with 10 minutes to go
Barcelona have not won the Spanish Super Cup since the change to a four-team format, with the first Saudi Arabia edition taking place in 2020.
Nemanja Gudelj scored a late equaliser as struggling Sevilla claimed a 1-1 draw at Real Betis in a derby which featured three red cards on Sunday.
A below-par Real Madrid dropped points in the title race with a 1-1 draw at home against Girona on Sunday in La Liga, with Rodrygo having a goal ruled out late on
Robert Lewandowski scored again as Barcelona defeated Sevilla 3-0 in La Liga on Saturday, while Real Madrid made it four wins from four with victory over Real Betis.
Real Madrid and Real Betis look to extend their perfect start to their La Liga season when they face off at the Estadio Santiago Bernabeu on Saturday