Premier League leaders Arsenal stretched their lead over Manchester City to seven points on Wednesday with a nervy win at Brighton, while Pep Guardiola's men were held to a costly 2-2 draw by Nottingham Forest.
Manchester City relied on the latest goal from recently signed forward Antoine Semenyo to secure a win that kept the pressure on Arsenal in the Premier League title race.
Real Madrid and Manchester City will face off in a Champions League knockout tie for the fifth season running.
Nico O'Reilly scored both goals for Pep Guardiola's team and extended Manchester City's unbeaten run in the league to five.
Mansfield produced the only shock of note so far in the fourth round by coming from behind to win 2-1 at top tier Burnley on Saturday.
Liverpool advanced to the fifth round of the FA Cup by defeating Brighton & Hove Albion 3-0 at Anfield.
Arsenal missed the chance to extend their Premier League lead to six points as Brentford rattled the Gunners in a 1-1 draw on Thursday to give Manchester City hope in the title race.
Pep Guardiola is hoping two rare free midweeks will refresh his "exhausted" Manchester City squad for the Premier League title run-in after beating Fulham 3-0.
Manchester City beat Fulham 3-0 to close in on Arsenal at the top of the Premier League on Wednesday, as Liverpool inflicted Sunderland's first home defeat of the season to ease the pressure on Arne Slot.
Manchester City can ramp up the pressure on Premier League leaders Arsenal by cutting the gap at the top to just three points when they face Fulham on Wednesday.
Erling Haaland's stoppage-time penalty earned Manchester City a dramatic 2-1 win at Liverpool on Sunday to reduce Arsenal's lead at the top of the Premier League back to six points.
Manchester City are pushing for Premier League glory after a mid-season stutter, strengthened by the arrivals of Antoine Semenyo and Marc Guehi
Manchester City will face Arsenal in the League Cup final after ending Newcastle's reign as holders with a first-half blitz in their 3-1 victory.
Manchester City boss Pep Guardiola has vowed to keep speaking out on humanitarian issues because of the "hurt" caused to the victims of global conflicts.
Manchester City's Premier League title challenge hit a fresh stumbling block as Dominic Solanke's acrobatic strike salvaged a 2-2 draw for struggling Tottenham on Sunday.
Erling Haaland ended his 10-game wait for a goal from open play as Manchester City beat Galatasaray 2-0 on Wednesday to book their place in the Champions League last 16.
Holders Paris Saint-Germain, Real Madrid and Liverpool are among the clubs battling for direct passage to the last 16 of the Champions League going into the final round of the league phase this week.
Pep Guardiola said his success at Manchester City has come in spite of refereeing decisions going against his side in a tirade following Saturday's 2-0 win over Wolves.