Manchester City reduced Liverpool's lead at the top of the Premier League table to four points.
Gabriel Jesus struck four goals in a 9-0 thrashing of Burton Albion.
Arsenal have clinched the FA Cup a record 13 times while Manchester United have 12 titles from the competition.
Real Madrid have reportedly agreed to pay 17 million euros up front for Brahim Diaz, whose deal at Manchester City was set to expire in June.
Manchester City recently suffered back-to-back defeats against Crystal Palace and Leicester City.
David Silva put City ahead after 10 minutes but they passed up a number of chances to add to the lead.
Manchester City now trail Liverpool by 10 points.
In the other clashes, Manchester United beat Huddersfield 3-1 and Tottenham thrash Bournemouth 5-0.
Jeffrey Schlupp, Andros Townsend and Luka Milivojevic were the goal scorers for Crystal Palace.
Pep Guardiola's side took the lead when Kevin De Bruyne marked his return from injury with a fine finish in the first half at the King Power Stadium.
Barcelona will take on Olympique Lyonnais in a relatively easy tie.
The win over Everton, moved Manchester City two points ahead of Liverpool, who host Manchester United on Sunday.
Manchester United have an impressive recent record against Liverpool, unbeaten in eight league games.
Leroy Sane secured victory by converting Raheem Sterling's pass on the hour mark.
Liverpool now lead City by a point after Mohamed Salah's hat-trick secured an impressive 4-0 win at Bournemouth.
Jose Mourinho's troubled relations with star midfielder Paul Pogba and other players have been an unwanted sideshow to a stuttering season.
Chelsea are currently in fourth place, 10 points adrift of Premier League leaders Manchester City after 15 games.
Chelsea and Arsenal are now tied on 31 points in fourth, still eight clear of United in eighth.