Languishing in 16th place in the Premier League, Tottenham are just one point above the relegation zone after Thursday's shambolic 3-1 home defeat against Crystal Palace.
Tottenham's Premier League survival hopes took another blow with a 3-1 loss to Crystal Palace on Thursday.
Arsenal reestablished a five-point lead at the top of the Premier League as the Gunners overcame 10-man Chelsea 2-1 on Sunday, while Benjamin Sesko fired Manchester United up to third with victory over Crystal Palace.
Arsenal midfielder Eberechi Eze tormented Tottenham again as his double revived the Premier League leaders' title bid in a 4-1 rout of their north London rivals.
Tottenham appointed Igor Tudor as interim manager on Saturday after Thomas Frank was fired three days ago.
Thomas Frank was fired by Tottenham on Wednesday after only eight months in charge and with his team just five points above the relegation zone in the Premier League.
Benjamin Sesko salvaged a 1-1 draw for Manchester United at West Ham as Michael Carrick's perfect start came to an end on Tuesday.
Bryan Mbeumo and Bruno Fernandes scored in each half at Old Trafford in a game that saw Spurs reduced to 10 men after captain Cristian Romero was sent off in the 29th minute.
The north Londoners have won just two of their last 15 Premier League games and sit in a disappointing 14th place.
Manchester City's Premier League title challenge hit a fresh stumbling block as Dominic Solanke's acrobatic strike salvaged a 2-2 draw for struggling Tottenham on Sunday.
Second-half goals from Randal Kolo Muani and Dominic Solanke helped Tottenham qualify directly for the Champions League last 16 on Wednesday with a 2-0 win at Eintracht Frankfurt.
Thomas Frank's job is under renewed threat after Tottenham dropped more points in a 2-2 draw at relegation-threatened Burnley on Saturday as Manchester City cut the gap to Premier League leaders Arsenal to four points.
Arsenal are hunting their fifth straight Premier League home win against old foes Manchester United this weekend as they look to stay clear of a faltering chasing pack.
Antoine Semenyo said goodbye to Bournemouth by clinching a dramatic 3-2 win that heaped pressure on under-fire Tottenham boss Thomas Frank on Wednesday.
Thomas Frank said the "boring Tottenham" taunts from his own club's fans were understandable after they were held to a dour 0-0 draw by Brentford on Thursday.
Manchester City trail Arsenal by four points at the top of the Premier League after failing to end Sunderland's unbeaten home record in a 0-0 draw on Thursday, while Liverpool were also held by Leeds.
Cristian Romero could be hit with an extended suspension after he was charged by England's ruling Football Association with failing to leave the field and acting in an "aggressive" manner when he was sent off against Liverpool last Saturday.
Alexander Isak is expected to be out of action for two months after fracturing his leg against Tottenham, with Liverpool manager Arne Slot accusing Tottenham's Micky van de Ven of making a "reckless challenge".