Arsenal advanced six points clear at the top of the Premier League as Bukayo Saka and Viktor Gyokeres put Fulham to the sword in a 3-0 win, while West Ham's defeat at Brentford offered Tottenham a lifeline in the battle for survival.
Tottenham confirmed on Monday that "heartbroken" Xavi Simons had ruptured an anterior cruciate ligament, forcing him out of the club's relegation scrap and the World Cup.
A first Premier League win in 2026 wasn't enough to lift Tottenham out of the relegation zone. Spurs beat relegated Wolves 1-0 on Saturday to hand Roberto De Zerbi his first victory as coach.
West Ham's 0-0 draw against Crystal Palace on Monday condemned Wolves to relegation from the Premier League and boosted their own survival bid to leave struggling Tottenham deeper in trouble.
West Ham climbed out of the Premier League relegation zone with a 4-0 win against Wolves on Friday that dumped Tottenham into the bottom three.
Tottenham appointed Roberto De Zerbi as the club's third manager of the season on Tuesday as they battle to avoid relegation from English football's top flight for the first time in nearly 50 years.
More than three-quarters of Premier League fans would like to see VAR scrapped and even more believe it has a detrimental impact on the matchday experience, according to a survey by the Football Supporters' Association (FSA).
Tottenham parted company with coach Igor Tudor by mutual consent on Sunday after just seven games in charge as they battle to stay in the Premier League.
Tottenham suffered a potentially seismic 3-0 defeat to Premier League relegation rivals Nottingham Forest on Sunday, failing to rise to a rallying call from their massed ranks of fans.
Relegation-haunted Tottenham Hotspur face a crunch clash against fellow strugglers Nottingham Forest as the fight for Premier League survival reaches boiling point.
Goals from Dominik Szoboszlai, Hugo Ekitike, Ryan Gravenberch and Mohamed Salah overturned a 1-0 first-leg deficit for Liverpool to set up a reunion with defending champions Paris Saint-Germain in the last eight.
Troubled Tottenham rescued a 1-1 draw at Liverpool thanks to Richarlison's late leveller, while Manchester United bolstered their bid to qualify for the Champions League with a 3-1 win against Aston Villa on Sunday.
Atletico Madrid took advantage of error-strewn Tottenham in the Champions League to rack up a 5-2 last 16 first leg victory on Tuesday.
Tottenham goalkeeper Antonin Kinsky was substituted after just 17 minutes of the Champions League last 16 first leg clash against Atletico Madrid on Wednesday after committing two errors leading to goals.
Languishing in 16th place in the Premier League, Tottenham are just one point above the relegation zone after Thursday's shambolic 3-1 home defeat against Crystal Palace.
Tottenham's Premier League survival hopes took another blow with a 3-1 loss to Crystal Palace on Thursday.
Arsenal reestablished a five-point lead at the top of the Premier League as the Gunners overcame 10-man Chelsea 2-1 on Sunday, while Benjamin Sesko fired Manchester United up to third with victory over Crystal Palace.
Arsenal midfielder Eberechi Eze tormented Tottenham again as his double revived the Premier League leaders' title bid in a 4-1 rout of their north London rivals.