Liverpool swept four points clear at the top of the Premier League as Mohamed Salah's masterclass inspired a memorable 6-3 rout of Tottenham
Tottenham manager Ange Postecoglou says he welcomes scrutiny but that some of the criticism directed at him is "offensive".
Chelsea take on Everton, while Liverpool face a tough tie against Tottenham.
Arsenal will take on Newcastle United in the other semi-final.
Tottenham boss Ange Postecoglou believes the job of a Premier League manager is harder than being Prime Minister, claiming coaches face "an election every weekend and either get voted in or out".
Premier League basement club Southampton on Sunday sacked manager Russell Martin after an embarrassing 5-0 home defeat to Tottenham.
Manchester United manager Ruben Amorim insists he did not speak to Manchester City about replacing Pep Guardiola at the Etihad Stadium before making his move to Old Trafford.
Rasmus Hojlund fired Manchester United to a late 2-1 win at Viktoria Plzen in the Europa League on Thursday, while Tottenham were held to a stalemate at Rangers.
Tottenham boss Ange Postecoglou returns to Glasgow on Thursday for a Europa League Battle of Britain against Rangers in desperate need of a victory to calm speculation over his future.
Chelsea roared back from two goals down to beat Tottenham 4-3 on Sunday, moving just four points behind Premier League leaders Liverpool after Arsenal were held by Fulham.
Manchester United marked Ruben Amorim's first game at Old Trafford with a 3-2 Europa League victory over Bodo/Glimt as Rasmus Hojlund netted a double, while Tottenham were held by Roma on Thursday.
Tottenham goalkeeper Guglielmo Vicario faces a spell on the sidelines after undergoing surgery on a fractured ankle.
Pep Guardiola conceded Manchester City are in uncharted territory after a 4-0 thrashing by Tottenham inflicted a fifth consecutive defeat on the English champions and ended a 52-game unbeaten home run.
Man City vs Spurs Live Streaming Premier League: Pep Guardiola and his men are on a four-game winless run, which started with a 2-1 defeat to Ange Postecoglu's Spurs in the League Cup.
Manchester United signed off Ruud van Nistelrooy's temporary stint in charge with a 3-0 win over Leicester on Sunday as Ipswich stunned Tottenham 2-1 for their first Premier League victory in 22 years.
Injury-hit Manchester City are desperate to snap their losing streak in their final Premier League game before the international break.
Victor Osimhen scored twice as Galatasaray inflicted a first Europa League defeat of the season on Tottenham with a 3-2 victory in Istanbul on Thursday, while Manchester United got their first win on the board by beating PAOK Thessaloniki.
South Korea are on course for the 2026 World Cup, sitting top of their group in the pivotal third Asian qualifying round with three wins and a draw.