Simone Inzaghi's team will care little about the result as the Scudetto was sealed weeks ago.
Udinese are level on 29 points with Sassuolo and sit just inside the drop zone ahead of their home fixture with Napoli on Monday night.
Inter Milan continued their march towards the Serie A title with Wednesday's 4-0 thumping of Atalanta which extended their league lead to 12 points
Dusan Vlahovic shot Juventus to within two points of Serie A leaders Inter Milan with a stunning double in Tuesday's 3-0 win over Sassuolo.
Atalanta beat Sassuolo 3-1 on Wednesday to qualify for the Italian Cup quarter-finals where they will meet AC Milan
Napoli continued a perfect start to their Serie A title defence with Sunday's 2-0 win over 10-man Sassuolo
Runaway leaders Napoli drew on Saturday as Italy awaits an explosive party in Naples where Napoli look certain to clinch a first title since the days of Diego Maradona.
AC Milan's season went even further off the rails on Sunday after a humiliating 5-2 home defeat at the hands of Sassuolo left them at risk of dropping out of the Champions League places
Lazio recovered from the early exit of injured captain Ciro Immobile to post a 2-0 win at Sassuolo on Sunday
AC Milan won their first Serie A title in 11 years on Sunday after beating Sassuolo 3-0 to snatch the crown from local rivals Inter Milan.
Inter Milan missed the chance to reclaim the Serie A summit on Sunday after falling to a 2-0 home defeat to giant-killers Sassuolo which allowed AC Milan to keep top spot.
Serie A: Benefiting from the stalemate between AS Roma and Inter Milan, champions Juventus powered up to fourth with a 3-1 win over 10-man Sassuolo.
Serie A: Rafael Leao scored his third league goal of the season in AC Milan's win over Sassuolo.
Serie A leaders Juventus continued to stutter towards a ninth straight league title as they threw away a two-goal lead before settling for a thrilling 3-3 draw at Sassuolo on Wednesday.
Maurizio Sarri's Juventus fell in the Italian Cup final to Napoli on penalties midweek, having also lost the Italian SuperCup to Lazio in December.
Serie A clubs unanimously voted on Friday to finish the 2019-20 season -- suspended since March 9 with Juventus leading Lazio by a point.
Italian Prime Minister Giuseppe Conte on Monday announced the suspension of all sporting events in the country, including the top-flight Serie A football league until April 3, as Italy grapples with the coronavirus crisis.
The matches between title-chasing Inter Milan and Sampdoria, Atalanta against Sassuolo and Hellas Verona versus Cagliari have been pushed back to avoid the spread of coronavirus.