Marcello Lippi's Chinese side finished as group runners-up having likewise already sealed their place in the last 16.
Paulo Bento will take no risks with his best player despite needing a win to finish top of Group C.
South Korea will be boosted by the arrival of Tottenham star Son Heung-min after their first two games.
Jang Hyun-soo admitted to giving false community service records required for his military service exemption.
The World Cup star is in Indonesia chasing a gold medal that would spare him a career-threatening spell of military service.
Mesut Ozi's father said his son had been "made the scapegoat" after Germany's World Cup exit and should quit the national team.
Suggestions on Twitter that the FIFA World Cup be restricted to 10 ten teams were greeted with laughter.
The British press made the most of Germany's elimination from the 2018 World Cup at the first-round stage for the first time since 1938.
South Korean social media were flooded by tens of thousands of messages from fans expressing joy and astonishment over a victory that had seemed utterly implausible before the match.
"Korea! Korea!" chanted fans in a Mexico City bar, leaping into the air and embracing when the Asian side scored a stoppage-time, VAR-assisted goal, and then a late second to seal the reigning champions' humiliating exitand allow Mexico to squeak through to the Round of 16.
Germany qualified for Russia with a perfect record of ten wins, but Hummels said the last time the team played well was when they wrapped up qualification late last year.
Sweden surged into the last 16 of the World Cup with a deserved 3-0 victory over a poor Mexico side, who still qualified ahead of Germany after the holders' loss to South Korea.
Germany's exit from the 2018 World Cup is the sixth time in the history of the competition that the reigning champions have failed to make it past the first hurdle.
Germany finished bottom of Group F after a 2-0 defeat against South Korea.
FIFA World Cup 2018, Highlights: Defending champions Germany crashed out after losing 0-2 to South Korea.
Germany must beat South Korea by two clear goals in Kazan on Wednesday to be sure of reaching the last 16.
Germany need to get maximum points vs South Korea to keep qualification race alive.