Enzo Maresca made 11 changes from the team that beat West Ham 3-0 on Saturday but could still start around 400 million pounds ($533 million) worth of talent.
Former Croatia international and national team coach Slaven Bilic guided West Brom to promotion in the 2019/20 season and has since managed in China.
Chelsea blew a two-goal lead in front of prospective owner Todd Boehly as Wolves snatched a dramatic 2-2 draw while Watford were relegated from the Premier League after just one season back in the top-flight.
Pep Guardiola saluted "fantastic" Gabriel Jesus after the Brazilian scored four times as Manchester City crushed Watford 5-1 to move four points clear at the top of the Premier League on Saturday.
Premier League: Liverpool beat Watford 2-0 thanks to goals from Diogo Jota and Fabinho.
Bukayo Saka starred as Arsenal leapfrogged Manchester United into the Premier League top four on Sunday with a 3-2 win at struggling Watford.
Manchester United's challenge for a top-four finish in the Premier League stumbled once more as Watford clung on for a 0-0 draw at Old Trafford to boost their hopes of survival.
Manchester United vs Watford, Premier League: Manchester United will be hoping to capture all three points against Watford at the Old Trafford Stadium in Manchester on Saturday.
Roy Hodgson is ready for the challenge of Watford's relegation dogfight after admitting he could not resist the "siren call from the mermaid".
Premier League: Claudio Ranieri was hired in October last year as Watford manager and replaced Xisco Munoz.
Premier League: Burnley manager Sean Dyche, speaking at a press conference on Monday, said only 10 first-team players took part in training that day before the club asked for the postponement.
AFCON: The tournament gets underway next Sunday in Cameroon and runs until February 6, clashing with the European club season.
Davinson Sanchez snatched a last-gasp winner as Tottenham beat struggling Watford 1-0 to extend Antonio Conte's unbeaten start on Saturday.
Premier League: Tottenham dropped two precious points against 10-man Southampton on Tuesday as West Ham hammered Watford 4-1 to turn up the heat in the race for a coveted top-four spot.
Watford manager Claudio Ranieri said his side have to learn to battle for their place in the Premier League after conceding twice in the final six minutes to lose 2-1 at Brentford.
Bernardo Silva backed up Pep Guardiola's claim he is the best player in the Premier League right now by scoring twice as Manchester City cruised to the top of the Premier League.
Premier League: Gabriel Jesus lashed on to a through ball from Fernandinho before crossing it into the path of Bernardo Silva, who made no mistake, side footing his volley from inside the box.
Ole Gunnar Solskjaer said he hopes to have left Manchester United in a better state than he inherited them three years ago after the Norwegian was sacked by the club on Sunday.