Napoli reached the last 16 of the Champions League on Tuesday after seeing off Braga 2-0 and ending a home hoodoo which had stretched back more than two months.
A single-goal defeat on Tuesday would still allow the ailing Italian champions, who are second in Group C and three points ahead of Braga, passage on goal difference
Jude Bellingham scored his third goal in as many Champions League appearances for Real Madrid as the Spanish side won 2-1 away to Braga in Portugal on Tuesday
Manchester United crashed to a second successive Champions League defeat on Tuesday, losing 3-2 at home to Galatasaray, while Lens stunned Arsenal 2-1.
Braga won 1-0 against Panathinaikos in Greece to secure a 3-1 aggregate success.
Kerzhakov met a cross from Hulk to net the winner which lifted the Russian club into second place in the group with four points. Porto slipped to third, one point behind Zenit.
The Portuguese coach has a contract with Real Madrid through the end of the 2015-16 season.
James Rodriguez's 90th-minute goal gave FC Porto a 2-0 win at third-place Braga to extend its unbeaten streak to 23 straight matches in all competitions and retain its share of the Portuguese league lead.
Manchester United became the third club to reach the Champions League knockout stages after coming from behind to beat Braga 3-1 and ensure they also top their group.
Manchester United staged a dramatic fightback from two goals down as Javier Hernandez's double inspired a 3-2 win over Braga in the Champions League on Tuesday.
European football's governing body UEFA on Wednesday fined FC Porto 20,000 euros ($26,344) for its supporters' "racist conduct" during a match against Manchester City.
Braga's run as Portuguese leader lasted just five days as a stoppage time goal saw it lose 2-1 to Benfica on Saturday, allowing Porto to go back to the top.
Atletico Madrid bought Colombia striker Radamel Falcao from FC Porto on Friday in a Portuguese and club record transfer deal of
Chelsea have appointed FC Porto boss Andre Villas-Boas as their new manager in a record-breaking deal, a club statement announced on Wednesday.
Chelsea target Andre Villas-Boas has opened the way for a move to the English Premier League by resigning as FC Porto coach, the Portuguese champions confirmed on Tuesday.
Falcao fired FC Porto to Europa League glory as the Colombia striker capped a remarkable campaign by clinching his side's 1-0 win over Braga in the all-Portuguese final in Dublin on Wednesday.
Unheralded Sporting Braga edged domestic rivals Benfica 1-0 in a nerve-jangling semi final second leg on Thursday to set up an all-Portuguese Europa League final with league champions FC Porto.
Portugal coach Paulo Bento has given FC Porto midfielder Ruben Micael another chance to make his debut for the national side after naming a 23-man squad for upcoming friendlies against Chile and Finland.