A record-breaking 60 meetings saw Novak Djokovic come out on top 31 times, although Rafael Nadal won 11 of 18 Grand Slam matches.
Novak Djokovic implored long-time adversary Rafael Nadal to put off his planned retirement after defeating the Spaniard Saturday in what was likely to be the final chapter of their "amazing rivalry".
Novak Djokovic vs Rafael Nadal LIVE Streaming Six Kings Slam Live Telecast: When And Where To Watch
World number one Jannik Sinner defeated 24-time Grand Slam champion Novak Djokovic 7-6 (7/4), 6-3 on Sunday to win the Shanghai Masters.
Novak Djokovic shrugged off physical discomfort to set up a blockbuster Shanghai Masters final with world number one Jannik Sinner.
Rafael Nadal's rivalry with Roger Federer will forever be remembered for a series of classic clashes, but his head-to-head record against Novak Djokovic featured more matches
Novak Djokovic hailed Rafael Nadal's "legacy" while Carlos Alcaraz said hearing about his fellow Spaniard's retirement was "painful".
Rafael Nadal's retirement announcement on Thursday left Novak Djokovic as the last man standing from tennis's golden era but with major question marks over the Serb star's own long-term future in the sport.
Rafael Nadal won his first major title at his first French Open, beating Mariano Puerta in the final two days after turning 19.
Coco Gauff joined Novak Djokovic and Carlos Alcaraz on the US Open scrap-heap Sunday as the defending champion crashed out to Emma Navarro in a blizzard of mistakes.