AC Milan striker Christian Pulisic is among five players rested from the United States national team ahead of Tuesday's friendly in Mexico
The record-breaking tally comes with the regular season still to be completed. Sixteen more matches are due to take place before the season wraps up on October 19.
US soccer icon Alex Morgan bade an emotional farewell to football on Sunday as she played the final game of her glittering career before heading into retirement.
The USA came into the Olympics with a rejuvenated squad and a point to prove after a poor showing at last year's World Cup, when they were eliminated in the last 16.
World Cup holders Spain and four-time gold medallists the United States are on course for a showdown in the Olympic women's football final with the two heavyweights favourites to win
The Copa America final between Argentina and Colombia started 82 minutes late as the security at the stadium could not ensure safe entry of fans.
USA were knocked out after a 1-0 loss to Uruguay, as Panama qualified ahead of them after a win over Bolivia.
A moment of madness from Timothy Weah left the USA's Copa America campaign hanging by a thread on Thursday as the hosts crashed to a shock 2-1 defeat to Panama, while Uruguay hammered Bolivia 5-0.
Christian Pulisic scored one goal and set up another as the United States launched their Copa America campaign with a clinical 2-0 Group C victory over Bolivia on Sunday.
The United States bounced back from their 5-1 defeat to Colombia to earn a morale-boosting 1-1 draw with Brazil in their final warm-up game before the Copa America on Wednesday.
United States coach Gregg Berhalter accused his players of lacking respect for Colombia after the South Americans romped to an emphatic 5-1 friendly victory over the Copa America hosts on Saturday.
Next year's 48th edition of the Copa America, featuring 10 South American nations and six North American teams, will be held in 14 venues across 10 US states, organizers said on Monday
Julian Nagelsmann got off to a winning start as Germany's coach on Saturday with his team securing a comfortable 3-1 win over the United States in a friendly
Forward Megan Rapinoe has broken her silence following United States Women's National Soccer Team's earliest-ever exit at the FIFA Women's World Cup.
USA were eliminated from the Women's World Cup following a penalty shootout loss against Sweden.
Sweden knocked two-time defending champions the United States out of the Women's World Cup on Sunday, winning their last-16 tie 5-4 on penalties.
Holders the United States squeezed into the last 16 of the Women's World Cup with a shaky 0-0 draw against debutants Portugal on Tuesday
Sophia Smith scored twice and set up another as a new-look United States launched their bid to win a third Women's World Cup in a row with a 3-0 victory over Vietnam on Saturday.