Juventus head to Milan having lost just one of their last 10 matches but Inter have won their last five league games.
Two goals from on-loan Donyell Malen drove Roma to a 2-0 win over Cagliari on Monday, lifting them level with fourth-placed Juventus in Serie A.
Trailing leaders Inter Milan by six points ahead of their trip to Turin, Napoli have to pick themselves up after a poor 1-1 draw at 10-man FC Copenhagen.
Paulo Dybala starred for Roma with a goal and an assist in Sunday's 2-0 win at Torino which boosted his team's Champions League hopes.
Roma scored three times in a one-sided first half to beat Genoa 3-1 on Monday and move into fourth place in Serie A.
Juventus have another chance to drag themselves back into the Serie A title discussion on Saturday when rivals Roma come to Turin with the other main contenders in Riyadh for the Italian Super Cup.
David Neres stroked home the only goal of a feisty game in the 36th minute at the Stadio Olimpico, as Napoli beat Roma 1-0.
Roma are surprise leaders of Serie A heading into Sunday's clash with Napoli, a fixture which will go some way to showing whether Gian Piero Gasperini's side are the real deal.
AC Milan also had Mike Maignan to thank for the three points as the France goalkeeper kept out Hakan Calhanoglu's penalty in the 74th minute.
Inter Milan were handed a 2-1 win at Verona by a late own goal on Sunday to move to within a point of stuttering Serie A leaders Napoli.
Paulo Dybala scored his first Serie A goal of the season to give Roma a 1-0 victory at Sassuolo on Sunday to lift them level with leaders Napoli.
Inter Milan moved top of Serie A on goal difference on Saturday after winning 1-0 at Roma, taking advantage of Napoli's shock 1-0 defeat at Torino.
Roma moved top of Serie A on Sunday after coming from behind to win 2-1 at Fiorentina, throwing down the gauntlet to Napoli and AC Milan.
Roma were allowed to have three separate attempts at the same penalty, but were sensationally denied by Lille goalkeeper Berke Ozer in their Europa League clash.
Gian Piero Gasperini has chosen Roma over Juventus who tried to convince him to move to Turin.
Gian Piero Gasperini is set to join Roma on a three-year contract with a net salary of five million euros a season as the capital club try to re-establish themselves in the Serie A top four.
Atalanta qualified for the Champions League on Monday by beating Roma 2-1 and mathematically securing a place in Serie A's top four.
Inter Milan's defence of their Serie A title was hit with a setback on Sunday as they lost 1-0 at home to Roma