Arsenal slowed Chelsea's charge for a Champions League place as Manchester City kept up their distant pursuit of Liverpool with victory at Sheffield United.
A slump in form from Frank Lampard's men has left the door open for Manchester United, Tottenham and Arsenal to secure a much-needed return to Champions League.
Chelsea and Manchester United secured comfortable wins in the race for the Premier League top four.
Pierre-Emerick Aubameyang's opening goal was cancelled out by a Jordan Ayew strike in the second half.
FA Cup Draw: Liverpool face a trip to either Bristol City of the Championship or Shrewsbury Town of League One as holders Manchester City take on Fulham.
Arsenal made Leeds pay for their profligacy with a host of wasted first-half chances before Reiss Nelson scored the winner 10 minutes into the second period.
Ole Gunnar Solskjaer launched a scathing attack on former Manchester United and Arsenal striker Robin van Persie for some of his recent comments.
Chelsea boss Frank Lampard is expected to make a big splash after being unable to sign players in the summer window due to the club's transfer ban.
Mikel Arteta got everything he asked for in his first win as Arsenal manager with a rampant first 45 minutes from the Gunners earning a 2-0 victory over Manchester United.
Just nine points separates ninth-placed Crystal Palace and third from bottom Aston Villa. Norwich City are currently bottom of the Premier League table with 13 points.
Arsenal vs Chelsea: Pouncing on Arsenal goalkeeper's mistake, Jorginho scored in the 83rd minute to spark a Chelsea fightback that climaxed in Tammy Abraham firing home with three minutes left.
Chelsea have now lost to West Ham, Bournemouth and Southampton in their last four home league games.
Carlo Ancelotti and Mikel Arteta got a glimpse of the problems that lie ahead in their new jobs as they watched Everton and Arsenal share a dreadful 0-0 draw.
Mikel Arteta was hired by Arsenal on Friday after agreeing a three-and-a-half-year contract to replace the sacked Unai Emery.
Mikel Arteta signed a three-and-a-half year contract and ends a three-year stay as Pep Guardiola's assistant at Manchester City.
The Tottenham vs Chelsea Premier League clash will pit Frank Lampard against his former manager Jose Mourinho.
Manchester United will take on Club Brugge in the last 32 of the Europa League while struggling Arsenal will face Greek side Olympiakos.
Mesut Ozil, a German national of Turkish origin, condemned China's crackdown on Muslim minorities in the western region of Xinjiang in a tweet on Friday.