India's challenge ended at the Aegon International, the last tournament in the lead up to Wimbledon, with the defeats of Sania Mirza and Leander Paes in their respective events.
In the women's doubles, third seeded pair of Sania and Cara Black recovered from a first set rout but ended up losing 1-6 6-3 7-10 against the unseeded Taipei pair of Hao-Ching Chan and Yung-Jan Chan in the quarterfinals.
Paes, who had partnered with Aisam-ul-Haq Qureshi, also lost at the quarterfinal stage in the men's event.
The second seeded Indo-Pak pair lost 3-6 4-6 to Treat Huey of Philippines and Briton Dominic Inglot.
Wimbledon championships, the third Grand Slam of the season, begins Monday.
Sania and Cara have been seeded fourth while Paes and Radek Stepanek are seeded fifth in the men's doubles.
Bopanna and Qureshi are seeded eighth.