Serena Williams' Wimbledon comeback is over after the American legend pulled out of the doubles due to a knee injury on Saturday.

Serena and Venus Williams team up in the women's doubles at Wimbledon on Saturday for the first time since winning their sixth title 10 years ago.

Serena Williams received wild card invitations from Wimbledon organizers to play both singles and doubles with sister Venus Williams.

Serena Williams' comeback hit a bump Tuesday with a loss in her opening-round doubles match at the Berlin Open

Even at a combined age of 90, opponents should still be wary of facing the Williams sisters at Wimbledon.

Venus Williams set a record just by starting her first-round match at the Australian Open, a testament to her endurance and longevity at the highest level of tennis.

Seven-time Grand Slam champion Venus Williams said Saturday she was "up for the challenge" as she gets set to become the oldest woman to play at the Australian Open at age 45.

Coco Gauff and Venus Williams could meet in the second round of the Australian Open, another potential chapter in a tennis tale that started with a 15-year-old on her Grand Slam debut beating a seven-time major winner at Wimbledon.

The American will play her first Australian Open in five years and will be the oldest woman ever at the Melbourne tournament after being granted a wildcard.

Williams' last tournament was the US Open in August, not long after returning from a 16-month break.