American Ben Shelton came to the court with a pair of losses against 37-year-old qualifier Adrian Mannarino.

Stefanos Tsitsipas was booed after taking more than eight minutes between the third and fourth sets but dominated after his extended toilet trip to beat Adrian Mannarino 6-3, 6-4, 6-7 (4/7), 6-0 at Arthur Ashe Stadium.

Wimbledon 2021: Roger Federer was as his disarming best when he made light of an interviewer's question which the tennis star said had challenged his command on the English language.

Wimbledon 2021: Roger Federer survived a huge Wimbledon scare when French opponent Adrian Mannarino was forced to retire injured at the start of the fifth set of their first round tie with the scores level at 6-4, 6-7 (3/7), 3-6, 6-2 0-0 (15/0).

Novak Djokovic called for the doctor during the second set against Adrian Mannarino but put aside his discomfort to progress 4-6, 6-2, 6-1.

Roger Federer played a fluent forward defensive cricket shot during his Wimbledon match with Adrian Mannarino.

Top seed Roger Federer, 36, has now won 32 consecutive sets at Wimbledon.

Roger Federer survived a surprise test at the Swiss Indoors on Friday before making the semi-finals at his home event for the 14th time with a hard-fought 4-6, 6-1, 6-3 win over Adrian Mannarino.

Novak Djokovic will face the Czech Republic's Tomas Berdych on Wednesday for a semi-final spot, boasting a 25-2 career record over the 2010 Wimbledon runner-up.

Roger Federer, who won five consecutive U.S. Opens from 2004-08, next plays 19th-seeded Tommy Robredo of Spain. Win that, and Federer could face 12-time major champion Rafael Nadal in the quarterfinals in what would be the rivals' 32nd meeting