Andy Murray Stunned by Gabashvili in US Open Tuneup

British top seed Andy Murray suffered a stunning defeat in his first hardcourt warm-up match for the US Open, losing Wednesday to Teymuraz Gabashvili at the ATP and WTA Washington Open.

The 53rd-ranked Russian outlasted third-ranked Murray 6-4, 4-6, 7-6 (7/4) over two hours and 41 minutes to reach the third round at the ATP and WTA Washington Open.

Gabashvili, who was 3-22 against top-10 foes before the match, hit 30 winners and only made 15 unforced errors in making Murray the highest-ranked victim of his career, advancing to face the winner of a later match between Uruguay's Pablo Cuevas and Lithuania's Ricardas Berankis.

It was a shocking defeat for the 28-year-old Scotsman, who sparked Britain's Davis Cup team past France in July after a semi-final run at Wimbledon. Murray, the 2012 US Open and 2013 Wimbledon champion, was playing in the US capital for the first time since losing the 2006 final to France's Arnaud Clement.

Gabashvili, who lost to Murray last year at Shanghai in their only prior meeting, broke the Briton with a backhand winner to take the first set after 45 minutes.

The 30-year-old Russian denied him on a break chance with a service winner and held to 2-2.

Murray made the most of his next break chance in the seventh game, his running forehand lob setting up a Gabashvili forehand overhead smash that the Russian swatted wide to surrender a 4-3 edge.

Murray netted a forehand to give Gabashvili a break chance in the 10th game but the Russian sent a forehand volley long and two points later hit a backhand wide to hand the Scotsman the second set.

Murray broke Gabashvili at love in the ninth game of the third set and was two points from victory before surrendering a service break, a wide crosscourt backhand pulling the Russian level at 5-5.

After Murray hit a forehand winner for a 4-3 lead in the tie-breaker, Gabashvili won the final four points, the last on a backhand winner with a celebration fist pump seconds later.

US eighth seed Isner, coming off a third consecutive Atlanta title last week, blasted 17 aces without a double fault in advancing with a 6-3, 7-6 (7/5), triumph over Dominican Victor Estrella Burgos.

Argentina's Leonardo Mayer outlasted Slovenian Blaz Rola 7-6 (7/2), 6-7 (3/7), 6-4, to reach a third-round matchup against Japanese second seed Kei Nishikori.

Australia's Sam Groth ousted Serbian Viktor Troicki 6-3, 6-4 to book a third-round date with Spanish seventh seed Feliciano Lopez, who rallied to beat Aussie Lleyton Hewitt 4-6, 7-5, 6-3.

On the women's side, Australian second seed Samantha Stosur, the 2011 US Open champion, advanced to a quarter-final with a 6-1, 7-5 victory over American Irina Falconi. Stosur next faces Romania's Monica Niculescu, who rallied past American Lauren Davis 1-6, 6-1, 6-4.

French fifth seed Alize Cornet was upset 7-5, 4-6, 7-6 (7/4) by 19-year-old wildcard Louisa Chirico in a grueling three-hour test, the 128th-ranked American reaching the last eight after only winning her first WTA match Monday.

"They are definitely confidence boosting," Chirico said of her wins. "I definitely feel like I belong here."

Defending champion Svetlana Kuznetsova withdrew due to a lower left leg injury, advancing American Sloane Stephens into the quarter-finals against Chirico.

"I'm so sorry to have to do this but my body doesn't feel up to it," Kuznetsova said.