It means Spain's title race suddenly appears wide open, two months after Atletico Madrid sat 10 points clear of both Barcelona and Real Madrid, with a game in hand.
Barcelona's demolition of a Real Sociedad side with hopes of qualifying for Europe spoke volumes about where the momentum lies in the Spanish title race.
Luis Suarez will be key for Atletico Madrid if they are to turn around a 1-0 deficit against Chelsea at the Stamford Bridge.
Luis Suarez's penalty sent Atletico Madrid six points clear at the top of La Liga on Wednesday as the leaders survived a scare to beat a resurgent Athletic Bilbao 2-1.
La Liga: Atletico Madrid failed to make their authority count and Karim Benzema punished them in the 88th minute, his goal earning Real Madrid a 1-1 draw.
La Liga: Atletico Madrid gave renewed hope to their La Liga title rivals by losing 2-0 at home to Levante, and missing the chance to extend their six-point lead at the top of the table.
Luis Suarez shows no sign of letting up, the Uruguayan now with 11 goals in his last nine games and 16 for the season.
Lionel Messi underlined his worth to Barcelona by scoring a sensational free-kick on Sunday as the Catalans registered a 2-1 win over Athletic Bilbao.
Luis Suarez sent Atletico Madrid 10 points clear at the top of La Liga on Sunday by scoring a sensational free-kick and then a penalty in a pulsating 4-2 win over Cadiz.
Luis Suarez scored a brilliant team goal as Atletico Madrid came from behind to beat Valencia 3-1 on Sunday and move seven points clear at the top of La Liga.
Lionel Messi became the first foreigner to make 500 appearances in Spain's La Liga as Barcelona beat bottom side Huesca 1-0.
Luis Suarez struck a 90th-minute winner for Atletico Madrid as they defeated 10-man Alaves 2-1 on Sunday to move back above Real Madrid at the top of La Liga.
La Liga: Real Madrid failed to end their year with a win after 1-1 draw at Elche, while Atletico Madrid beat Getafe 1-0 to extend their lead at the top.
Luis Suarez scored twice from close range in a 3-1 victory for Atletico Madrid against Elche on Saturday to move Diego Simeone's side three points clear at the top of La Liga.
The country's health ministry fined the Uruguayan football federation USD 15,000 (12,650 euros) for "failure to respect health protocols" following the raft of infections.
Lionel Messi can talk to other clubs in January and leave for free when his contract expires in June, with Manchester City expected to make a renewed attempt to lure the 33-year-old away from Camp Nou.
Barcelona's salary cap for the 2020-21 season will be 382.7 million euros, down from 671.4 million euros last term, when they had the highest limit in La Liga.
The positive test also means Luis Suarez will miss his club Atletico Madrid's La Liga outing against Barcelona, which would have been the first time he ran out against his former team.