Zlatan Ibrahimovic scored 28 goals in 46 appearances during a stunning first season in England to help United win the Community Shield, League Cup and Europa League last season.
Zlatan Ibrahimovic might not be the only high-profile departure from Manchester United this summer.
Sweden qualified in Ibrahimovic's absence with a famous 1-0 victory over four-time world champions Italy in a two-legged playoff last November.
Zlatan Ibrahimovic's introduction as a second-half substitute proved crucial as Manchester United finally discovered a way to beat newly-promoted Brighton and Hove Albion.
The Manchester United manager has stubbornly refused to put a timeline on the absences of long-term injury victims Ibrahimovic and Paul Pogba, who suffered a hamstring tear in mid-September.
Zlatan Ibrahimovic has rejoined Manchester United on a one-year contract after the Swedish star's spell with the Premier League side was curtailed by a serious knee injury last season.
Marcus Rashford's stunning free-kick 23 minutes from time put Manchester United on the brink of reaching the Europa League final with a hard-fought 1-0 win at Celta Vigo.
The scrappy, sapping victory means Jose Mourinho's Manchester United remain on course to claim the only major trophy missing from the club's collection.
While Manchester United defeated Sunderland 3-0, Everton moved past Leicester City 4-2 in the Premier League on Sunday.
Jose Mourinho made the strong statement following injuries to key central defenders Chris Smalling and Phil Jones on England duty.
The three-game ban means Zlatan Ibrahimovic will miss Manchester United's FA Cup quarterfinal clash against Chelsea on Monday, March 13
Zlatan Ibrahimovic led with his right elbow as he clattered into Mings while the duo challenged for an aerial ball just before half-time.
Marcos Rojo put Manchester United ahead in the 23rd minute at Old Trafford, but Joshua King levelled from the spot five minutes before half-time following a foul on Marc Pugh by Phil Jones.
Following Manchester United's 3-1 win over Southampton in the League Cup final, Zlatan Ibrahmovic and Paul Pogba were both in a very jovial mood.
A day ahead of the EFL Cup final, a Manchester United fan took to Twitter to remind the official Liverpool account about the possibility of the Manchester club overtaking their major title haul
Zlatan Ibrahimovic scored a brace to help Manchester United win the EFL Cup by beating Southampton in 3-2 in the final at Wembley Stadium.
While Tottenham Hotspur thrashed Fulham 3-0 thanks to a hat-trick from Harry Kane, Manchester United edged past Blackburn Rovers 2-1 in the FA Cup.