Aston Villa striker Gabriel Agbonlahor on Friday withdrew from the England squad to face Spain and Sweden after sustaining a slight hamstring injury, officials confirmed.
Agbonlahor was sent back to Villa after an assessment early Friday by England medical staff who ruled he was unfit to train, an FA statement said. No replacement has been called up.
Meanwhile England's players took to the field at Wembley for training on Friday after holding two minutes' silence to mark Armistice Day.
It followed a row earlier this week over an FA request for England's players to be allowed to wear commemorative red poppies on their shirts for Saturday's prestige friendly against Spain at Wembley.
World governing body FIFA initially refused the request on the grounds that it could open the door to similar initiatives from other countries.
After protests from the British government and expression of dismay from Britain's royal heir Prince William, FIFA eventually agreed a compromise wear players are allowed to wear poppies on black armbands.