India's campaign ended at the Cincinnati Masters tennis tournament after Sania Mirza and Cara Black went down against Anabel Medina Garrigues of Spain and Kazakhstan's Yaroslave Shvedova in their women's doubles second round match here.
The fourth seeded Indo-Zimbabwean pair lost 3-6 3-6 in round two of the USD 2,567,000 hard court event in the run up to the US Open, the last Grand Slam tournament of the season.
Sania and Cara had got a bye in the first round.
Earlier, fifth seeds Leander Paes and Radek Stepanek were eliminated from the ATP Cincinnati Masters after their defeat against Vasek Pospisil and Jack Sock in the second round.
While the Indo-Pak pair of Rohan Bopanna and Aisam-ul-haq Qureshi had also bowed out of the tournament in the first round.