Mohamed Salah scored twice to take Liverpool nine points clear at the top of the Premier League by beating Bournemouth 2-0 on Saturday, while third-placed Nottingham Forest smashed Brighton 7-0.
Pep Guardiola's Manchester City have won four of their past five Premier League games to climb back into the top four after a miserable run of results.
Darwin Nunez struck twice in stoppage time to earn Liverpool a 2-0 win at Brentford and open up a seven-point Premier League lead on Saturday after Bournemouth ran riot in a 4-1 win at Newcastle.
Liverpool swept four points clear at the top of the Premier League as Mohamed Salah's masterclass inspired a memorable 6-3 rout of Tottenham
United's second successive loss after their League Cup exit at Tottenham on Thursday underlined Ruben Amorim's belief that their road back to the top will be long and arduous.
Bournemouth manager Andoni Iraola has paid tribute to Ruben Amorim's impact at Manchester United ahead of the Cherries' match at Old Trafford on Sunday.
Bournemouth's Enes Unal provided a dramatic climax to his side's 1-1 draw with West Ham on Monday as the Turkey forward's superb late free-kick cancelled out Lucas Paqueta's penalty
Manchester City suffered their first Premier League loss since December as Bournemouth stunned the champion
Erling Haaland fired Manchester City to the top of the Premier League as the striker sealed a 1-0 win against Southampton
Bournemouth's record signing Evanilson scored his first goal for the club as the Cherries beat Southampton 3-1 on Monday.
Liverpool moved to the top of the Premier League with a resounding 3-0 win over Bournemouth as Tottenham eased the pressure on Ange Postecoglou by beating Brentford 3-1 on Saturday.
Christopher Nkunku came off the bench to score the winner four minutes from time as Chelsea ground out a 1-0 win at Bournemouth on Saturday.
Noni Madueke hit a hat-trick as Chelsea crushed Wolves 6-2 to give Enzo Maresca his first Premier League win as Blues boss.
Phil Foden fired Manchester City to a 1-0 win against Bournemouth as the Premier League title chasers moved within one point of leaders Liverpool on Saturday.
Jota and Nunez stood up to be counted to secure a vital win at one of the form sides in the Premier League.
Arsenal's Premier League title challenge suffered another blow in a 2-1 defeat at Fulham while Tottenham beat Bournemouth 3-1.
Luton's Premier League clash against Bournemouth was abandoned on Saturday after Hatters captain Tom Lockyer collapsed during the second half.
Bruno Fernandes has apologised for Manchester United's embarrassing defeat against Bournemouth as the Portugal star admitted his side did not have enough effort or quality.