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Jose Mourinho admitted Manchester United had given him an FA Cup semi-final selection dilemma after their 2-0 win at Bournemouth on Wednesday.
Harry Kane limped off with his side trailing 1-0 at Bournemouth on Sunday, before Pochettino's men bounced back to win 4-1
Tottenham Hotspur move above Liverpool into third in the Premier League, but it was a bittersweet victory with concerns over Harry Kane's fitness.
Tottenham Hotspur ensured the focus switched back to the pitch, stunning Jose Mourinho's Manchester United with a performance full of attacking verve in a 2-0 win.
Eden Hazard quietened the debate surrounding Antonio Conte's future with the second-half goal that secured a 1-0 win at Bournemouth on Saturday.
Raheem Sterling celebrated his goal by throwing himself into the away section and was shown a second yellow card by referee Mike Dean.
Everton beat West Brom 3-0, Hull City defeated Swansea City 2-1 and Bournemouth edged past West Ham 3-2 in the Premier League on Saturday.
Zlatan Ibrahimovic led with his right elbow as he clattered into Mings while the duo challenged for an aerial ball just before half-time.
Marcos Rojo put Manchester United ahead in the 23rd minute at Old Trafford, but Joshua King levelled from the spot five minutes before half-time following a foul on Marc Pugh by Phil Jones.
Manchester City closed the gap on Chelsea to eight points following their win over Bournemouth to keep alive their hopes of winning the title
Bournemouth captain Simon Francis was shown a straight by referee Michael Oliver in the 82nd minute for his challenge on Arsenal midfielder Aaron Ramsey
Chelsea, Manchester City and Manchester United all notched comfortable wins on Monday, while Arsenal had to dig deep for a 1-0 win over West Brom
Arsenal would have provisionally supplanted leaders Chelsea on goals scored with victory and took a 20th-minute lead when Alexis Sanchez's free-kick deflected in off Williams.
Nathan Ake scored late into injury time as Bournemouth came back from 1-3 down to stun Liverpool 4-3 in a Premier League clash on Sunday
Kevin de Bruyne put Premier League leaders Manchester City ahead with a clever 15th-minute free-kick beneath the defensive wall and also played a part in goals for Kelechi Iheanacho, Raheem Sterling and Ilkay Gundogan.
Zlatan Ibrahimovic, Juan Mata and captain Wayne Rooney were on target as Manchester United recorded a straightforward win over Bournemouth, whereas Philippe Coutinho scored twice in Liverpool's 4-3 win over Arsenal
Goals from Wayne Rooney, 18-year-old Marcus Rashford and substitute Ashley Young secured the three points, which was enough to lift Manchester United above Southampton into fifth place in the Premier League
Army bomb disposal experts carried out a controlled explosion at Manchester United's Old Trafford stadium of a suspicious package which was later revealed to be a dummy left behind by a private security company following a training exercise