Maria Sharapova was knocked out of the US Open in the fourth round on Monday, losing 6-4, 6-3 to Spanish birthday girl Carla Suarez Navarro.
Venus Williams, who at 37 is the oldest player in the women's draw, has played sparingly this year but is just beginning to step up her game
Venus Williams, aged 36, is the oldest to make the last eight at Wimbledon since 37-year-old Martina Navratilova's run to the final in 1994
The hard-fought victory, over one hour and 51 minutes, will allow Carla Suarez Navarro climb five places to become the world number six.
Agnieszka Radwanska defeated 10th seed Carla Suarez 6-1, 6-3 in the Australian Open last-eight clash to enter her fifth career Grand Slam semi-final.
Carla Suarez bounced back from a disastrous start to come through the testing encounter 0-6, 6-3, 6-2 on Rod Laver Arena and will play Poland's Agnieszka Radwanska in the last eight.
The fourth seed Angelique Kerber was simply too strong for Carla Suarez Navarro, taking 75 minutes to win 6-2, 6-3.
Sania Mirza and Martina Hingis defeated Garbine Muguruza and Carla Suarez Navarro 6-0, 6-3 in the WTA Finals title clash.
Maria Sharapova went past Spain's Carla Suarez to win her third Italian Open crown. This latest success in Rome came after Sharapova claimed her second successive title in 2012 with victory over Li Na.
Carla Suarez, whose only tournament win to date was at Oeiras in 2014, defeated both Jelena Jankovic of Serbia and Czech fourth seed Petra Kvitova on her way to a last-four match-up with Halep in Rome.
US Open finalist Caroline Wozniacki will take on eighth-seeded Carla Suarez Navarro of Spain in Friday's quarterfinals at Tokyo.
World number one Williams, a 16-time Grand Slam winner seeking her fifth US Open crown and her ninth title of the year, dispatched 18th seed Carla Suarez Navarro 6-0, 6-0, in 52 minutes on the Spaniard's 25th birthday.
Kvitova, 2011 champion, is the only WTA player born in the 1990s to win a Grand Slam tournament.
The world number one, who will claim her 51st WTA title if she triumphs this weekend, will meet the winner of the quarter-final between Jelena Jankovic and Simona Halep.
Pavlyuchenkova has been working with Hingis officially for just a few weeks and the analytic game style and fighting determination of Switzerland's five-time grand slam champion may be rubbing off on the 21-year-old right-hander.
Fifth-seed Petra Kvitova of the Czech Republic later enjoyed a 7-5, 6-7(0/7), 6-3 win over wild-card Annika Beck, but only after the German put up a tough fight in the second set.
Sharapova, whose French Open triumph last year gave her a career Grand Slam, wasn't at her best against the Spaniard ranked 21st in the world, but she battled through to book a clash with either 14th-seeded Italy Roberta Vinci or Spain's Lara Arruabarrena-Vecino.