The previous longest US Open match was Stefan Edberg's victory over Michael Chang in the 1992 semi-finals, which lasted five hours and 26 minutes with Edberg winning 6-7 (3/7), 7-5, 7-6 (7/3), 5-7, 6-4.
Andy Murray is in the form of his career having already won a second Wimbledon title, a second Olympic gold medal and reached the finals of the Australian and French Open this season
World No.1 Serena Williams dominated Sweden's Johanna Larsson 6-2, 6-1 in the US Open third round match to surpass Martina Navratilova for most Grand Slam wins by a woman with 307 victories
Stan Wawrinka, a semi-finalist in 2013 and 2015, saved the match point at 5/6 down in the fourth set tiebreak to break the will of Dan Evans in a four-hour epic encounter at the US Open
Novak Djokovic lost the first two sets against Sam Querrey before persistent rain then saw the match postponed until Saturday. On the other hand, Roger Federer advanced to fourth round with a thumping win over Daniel Evans
Nishikori made 38 unforced errors and failed on seven of his nine break-point chances, including all five he managed in the final set, to fall after one hour and 57 minutes.