Russell lost the first three points of the deciding tiebreaker before rallying to reach his second career ATP semifinal. He raised both arms in triumph when Sijsling hit a backhand return long and wide.
Martin Alund of Argentina wore down Lleyton Hewitt of Australia 4-6, 6-3, 6-1 on Wednesday in the U.S. Men's Clay Court Championships before rain washed out the rest of the day's schedule.
The No. 5-seeded Berdych made only half of his first serves on Monday, but took advantage of 42 unforced errors from Russell to break the American six times.
Sam Querrey of the United States won the Farmers Classic for the third time in four years, downing Lithuania's Ricardas Berankis 6-0, 6-2 on Sunday at the Los Angeles Tennis Center.
Two-time champion Sam Querrey won his opening match in the Farmers Classic, beating Igor Sijsling of the Netherlands 6-2, 6-2 on Wednesday at the Los Angeles Tennis Center.
Qualifier Michael Russell took advantage of the ailing Mardy Fish for a 6-3, 6-1 victory Thursday in the second round of the U.S. Men's Clay Court Championship.
Andy Roddick held on to avoid a first-round upset at the U.S. Open, beating 96th-ranked Michael Russell 6-2, 6-4, 4-6, 7-5 on Wednesday night.
Continuing their good run, Somdev Devvarman and Treat Conrad Huey moved to the semifinals of the ATP Farmers Classic with a comfortable straight sets win over Gilles Muller of Luxembourg and Briton Jamie Murray.
India's Somdev Devvarman and Treat Conrad Huey of Philippines took out the top seeded Brazilian pair Marcelo Melo and Bruno Soares 6-3, 6-4 to enter the men's doubles quarter-finals of the $619,500 Farmers Classic tennis tournament.
Juan Martin del Potro battled back in the second set to beat James Blake 6-4, 7-6 (3) on Wednesday to reach the quarter-finals of the Farmers Classic.