Chelsea failed to take advantage of another Liverpool stumble in the race to qualify for next season's Champions League on Saturday, hammered 3-0 by Everton to remain outside the top five.
Max Dowman became the Premier League's youngest scorer at 16 years, 73 days, netting a stoppage-time goal for Arsenal in a 2-0 win over Everton.
Arsenal boss strongly defended his forward at his pre-match press conference on the eve of Saturday's home league match against David Moyes's Everton.
Pep Guardiola believes Manchester City's Premier League title challenge "will be over" if they fail to beat resurgent West Ham on Saturday.
Benjamin Sesko is yet to start in Michael Carrick's six games but has hit top form since Ruben Amorim was sacked in last month.
Everton striker Thierno Barry extended his hot streak with a late equaliser to rescue a 1-1 draw against lowly Leeds in the Premier League on Monday.
Aston Villa's Premier League title challenge suffered a huge blow in a 1-0 defeat against Everton, while Newcastle's push towards the top four was derailed by a 0-0 draw at Wolves on Sunday.
Viktor Gyokeres ended a barren goalscoring run from the penalty spot to send Arsenal back top of the Premier League with a hard fought 1-0 win at Everton.
Enzo Maresca said he had suffered his "worst 48 hours" since joining Chelsea after a 2-0 win at home to Everton on Saturday as he lamented a lack of support.
Everton survived an astonishing moment of madness at Old Trafford on Monday when Idrissa Gueye was sent off for slapping teammate Michael Keane to beat Manchester United 1-0.
Sunderland came back from a goal down to draw with Everton 1-1 and moved into fourth spot in the Premier League on Monday.
Thomas Frank's side extended their impressive away form thanks to Dutch defender Van de Ven's first-half double and a late Pape Sarr header.
Newcastle beat Nottingham Forest 2-0 to extend Ange Postecoglou's wait for a win, while Crystal Palace's 19-game unbeaten run was ended by Jack Grealish's late winner for Everton on Sunday.
Portuguese manager Nuno Espirito Santo picked up a point in his first match as West Ham manager after replacing Graham Potter.
Liverpool stretched their perfect Premier League start to maintain their stranglehold of the Merseyside derby with a 2-1 win over Everton and open up a six-point lead at the top of the table.
Liverpool manager Arne Slot thanked Everton for the support they showed their Merseyside rivals after Diogo Jota's tragic death in July.
Everton manager David Moyes said Liverpool have earned the right to spend a record amount in the transfer window as he aims to bridge the gap between the Merseyside rivals.
Manchester United remain without a Premier League win this season after being held 1-1 at Fulham on Sunday.