Mexican side Monterrey sent Lionel Messi and Inter Miami crashing out of the CONCACAF Champions Cup on Wednesday after completing a 5-2 aggregate victory in their quarter-final clash.
Gerardo Martino fielded a heavily second-string line-up with Lionel Messi's former Barcelona team-mates Luis Suarez, Sergio Busquets and Jordi Alba also on the bench.
Inter Miami were beaten 6-0 few nights ago at the hands of Cristiano Ronaldo's Al-Nassr, with Lionel Messi making a cameo off the bench.
FC Cincinnati led the way into the Major League Soccer playoffs on Wednesday as the slim post-season hopes of Lionel Messi's Inter Miami took a hit with a goalless draw against Nashville
In his first game against a Major League Soccer club, Messi was simply too much for Atlanta to cope with.
Lionel Messi announced his arrival at Inter Miami in style as the World Cup-winner scored in stoppage time to hand his team all three points in a Leagues Cup group fixture against Mexican side Cruz Azul on Saturday.
Lionel Messi made a Hollywood start to his career in America, scoring a last-second winner in his debut game for Inter Miami on Friday.
Martino, former coach of Messi with Barcelona and Argentina, said he had spoken to the seven-times Ballon d'Or winner and former Spain midfielder Busquets about their impending move to the Major League Soccer club
Busquets has been a central part of Barcelona's successes in the past 15 years, including nine Spanish league titles and three Champions League triumphs.
Sergio Busquets will leave Barcelona in June at the end of his contract, the midfielder confirmed Wednesday, ending a highly successful era at the club