The Uruguayan lineup announced Thursday was assembled by coach Oscar Tabarez, who is about to renew his coaching contract, but will not be able to attend the September friendlies for health reasons.
Uruguay captain Diego Lugano had said before their Confederations Cup semi-final against Brazil that striker Neymar is 'talented at winning free-kicks'.
Lugano had a clear message for Enrique Osses, who will referee the match in the Mineirao Stadium. "Neymar can feign a foul so we must be watchful that nobody is fooled by his ability," the Paris Saint-Germain defender said.
The Spaniards dominated throughout but after Pedro Rodriguez's opener deflected had cause to be grateful to Pedro Soldado's 32nd-minute clincher as Luis Suarez netted a late freekick for the Uruguayans.
Handily for Mourinho it was Albiol who got Madrid off to the perfect start as he got on the end of Luka Modric's corner to turn in his first league goal in four years with the club.