Rashid returned figures of 9-0-41-5 as the UAE, after electing to bat first, were bowled out for 177.
Calum MacLeod starred for Scotland with a spectacular unbeaten 157 that helped his team beat Afghanistan by seven wickets.
Afghanistan will take on Scotland in their opening match at the Bulawayo Athletic Club on Sunday, 4 March.
The Asian side dominated the match, which was reduced to 35-overs-a-side, to win by 29 runs on DLS method.
The World's No.1 ODI and Twenty20 International bowler, Rashid will lead Afghanistan after regular skipper Asghar Stanikzai was diagnosed with appendicitis.
Rashid Khan and India's pace sensation Jasprit Bumrah took the joint-top position among ODI bowlers.
Virat Kohli became only the second batsman to cross the 900-point mark in both Tests and ODIs on the ICC rankings.
Leg-spinner Rashid Khan starred as Afghanistan wrapped up a dominant 4-1 series win over Zimbabwe on Monday, cruising to a 146-run victory in the fifth and final one-day international at Sharjah.
Afghanistan scored 333/5 and restricted Zimbabwe to 179 in the 1st ODI, while Zimbabwe did exactly that in the 2nd.
Mohammad Nabi top-scored with a 26-ball 45 as Afghanistan finished on 158-9 from their 20 overs despite losing six wickets for 18 runs, with Zimbabwe falling short on 141-5.
Rashid Khan was signed by Sunrisers Hyderabad for 1.41 million dollars in last month's Indian Premier League auction.
78 players were sold on Day 1 of the IPL Auction 2018
Rashid has produced eye-catching performances in the world's top T20 leagues, most recently in the seventh season of the Big Bash League for the Adelaide Strikers.
The Afghan leg-spinner is one of the biggest prospects in international cricket.
Rashid has produced eye-catching performances in the world's top T20 leagues, most recently in the seventh season of the Big Bash League for the Adelaide Strikers. In six BBL matches, Rashid has picked up 11 wickets. Impressively, he is yet toconcede more than six an over in a BBL match this season.
The Afghanistan players, scheduled to play their first-ever test in India, are showing their quality to the world while playing in the Big Bash League.
Rashid, the first Afghan to play in the BBL Twenty20 competition, starred in the Strikers' 53-run win over Sydney Thunder in Adelaide.
Virat Kohli showered accolades on the Afghanistan cricket team and praised the efforts of the players for their relentless pursuit to play brilliant cricket amid worldly distractions.