Andy Roddick lost to South Africa's Kevin Anderson 4-6, 5-7 in the first round of the China Open on Monday, a defeat the sixth-seeded American called "unacceptable."
On the women's side, top-ranked Caroline Wozniacki rallied from a set down to beat Lucie Hradecka of the Czech Republic 3-6, 6-0, 7-5.
Roddick managed to handle Anderson's huge serve but struggled with his own and was broken in the seventh game to go one set down. The second set brought more of the same. While Roddick evened things up at 5-5, Anderson's momentum carried him through.
"If I break twice and don't win a set that says my serve isn't on," Roddick said. "It's unacceptable."
Wozniacki, the defending champion, was troubled at the start against another big-serving opponent - Hradecka had nine aces to the Dane's two. But Wozniacki improved in the second set as Hradecka's first serves increasingly hit the net, saving eight of 12 break points for the match.
"It wasn't a pretty match," Wozniacki said. "But I'm through and that's what's most important."
Third-seeded Klara Zakopalova of the Czech Republic defeated Nadia Petrova of Russia 6-3, 6-7 (3), 6-1, while Maria Kirilenko of Russia beat Julia Goerges of Germany 7-6 (9), 6-3.
Serbia's Ana Ivanovic downed Russia's Svetlana Kuznetsova, 6-2, 6-3, and Italy's Flavia Pennetta defeated China's Peng Shuai, 7-6 (6), 7-5.
Wild-card entry Zheng Jie of China outlasted Alberta Brianti of Italy 4-6, 6-1, 7-5; qualifier Virginie Razzano of France defeated Gisela Dulko of Argentina 6-2, 6-3; and Tamira Paszek of Austria beat Petra Cetkovska of the Czech Republic 1-6, 6-4, 6-2.
Among the men, Marin Cilic of Croatia defeated Chinese wild card Di Wu 6-2, 6-0; Feliciano Lopez of Spain beat Marsel Ilhan of Turkey 6-2, 7-6 (6); Fernando Verdasco of Spain topped Michael Llodra of France 6-2, 6-4; Florian Mayer of Germany ousted Albert Ramos of Spain 6-2, 6-4; and Flavio Cipolla of Italy defeated Alexandr Dolgopolov of Ukraine 6-1, 1-6, 6-0.