Alcaraz and Tsitsipas will face each other in the French Open quarter-finals.
Novak Djokovic held off a late rally from his American opponent on Court Philippe Chatrier to clinch a 6-3, 6-2, 7-6 (7/1) victory
The 21-year-old Czech was knocked out in the first round at the four majors last year but was too hot for the sixth-seeded Canadian on Margaret Court Arena, winning 4-6, 6-3, 7-6 (7/2), 7-6 (7/3)
Australian qualifier Alexei Popyrin stunned second seed Felix Auger-Aliassime in the first round of the season-opening Adelaide International on Monday.
Rising Canadian star Felix Auger-Aliassime said Saturday he was determined to "improve and improve" in a bid to keep riding the wave of success he enjoyed over the closing stages of 2022.
Rafael Nadal says he is "going to die" trying to return to the level of tennis that saw him capture a record 22 Grand Slam singles titles after his hopes of a first ever ATP Finals title
Casper Ruud got his ATP Finals off to a winning start on Sunday with a straight-sets victory over Felix Auger-Alissime, 7-6 (7/4), 6-4
Danish teenager Holger Rune defeated the in-form Felix Auger-Aliassime 6-4, 6-2 on Saturday to reach the first Masters final of his career in Paris
World number one Carlos Alcaraz retired from his Paris Masters quarter-final against Holger Rune on Friday with an abdominal injury, while Felix Auger-Aliassime stretched his winning run to 16 matches
Rafael Nadal set up a blockbuster French Open quarter-final against world number one Novak Djokovic on Sunday when he defeated Felix Auger-Aliassime in a five-set fourth round epic.