Rory McIlroy finished the tournament on 18 under, four shots clear of Xander Schauffele, who posted a closing 70 to finish on 14 under.
A statement from the PGA Tour said four fans were injured after two lightning strikes hit trees near the 16th tee at East Lake Golf Club in Atlanta, showering debris over nearby fans.
Tiger Woods seeks his first major triumph since the 2008 US Open.
Rory McIlroy, who has had a sensational start to the year, figures to be tested at Augusta National by resurgent Tiger Woods.
Tiger Woods, a 14-time major champion seeking a 4th WGC Match Play title, defeated Rory McIlroy in a morning knockout match only to fall to the 50th-seeded Dane.
Padraig Harrington played in six successive Ryder Cups from 1999 and was on the winning team on four occasions.
Italy's Francesco Molinari became the first European and only the fourth player ever to go 5-for-5 in a Ryder Cup.
This will be only the second time that the Ryder Cup is staged outside of Britain and Ireland after Spain's Valderrama in 1997.
Jordan Spieth shot a superb six-under-par 65 in benign conditions on Saturday to catapult himself up the leaderboard.
Tommy Fleetwood is dreaming of becoming the first English golfer to lift the Claret Jug since Nick Faldo in 1992.
Rory McIlroy laid the foundations for a two-stroke victory in the Deutsche Bank Championship over England's Paul Casey with a bewitching front nine performance, sinking five birdies to be five under at the turn
Rory McIlroy fired a one-under par 69 in the second round of the PGA Championship at Baltusrol, but a birdie-less 74 on Thursday proved too much to overcome and he finished one shot beyond the cut line
Rory McIlroy, who leads a host of the sport's biggest names to have withdrawn in controversial circumstances from next month's Rio Olympics, is bidding to win his fifth major and second Open after his victory at Hoylake in 2014
Jordan Spieth's choice not to travel to Brazil means none of the world's top four golfers will be competing in Rio after Jason Day, Dustin Johnson and Rory McIlroy had previously pulled out due to Zika virus fears
Fears over the Zika virus have been cited by a number of top golfers, including Rory McIlroy, who have pulled out of the 2016 Rio Olympics
Jason Day, Rory McIlroy are prominent golf stars who have cited mosquito-borne Zika virus as the reason behind their pullout from the quadrennial sporting event
Rory McIlroy has withdrawn from the 2016 Rio Olympics due to the Zika virus, denting Ireland's chances of a potential medal in the games
Anirban Lahiri and Jeev Milkha Singh failed to make the cut after the end of the second round of the US PGA Open championships.