Chuck Blazer is resigning as secretary general of the Confederation of North, Central American and Caribbean Association Football (CONCACAF), just four months after blowing the whistle on alleged corruption in the Caribbean Football Union (CFU).
The 66-year-old American plans to quit his post Dec 31 to pursue other career opportunities in the game.
"My passion (for the game) is undiminished and it is time for me to explore new challenges within this wonderful sport," he said.
"Running a governing body has been an incredibly fulfilling job, but there are so many other areas of the sport where as a senior executive, I will make a great impact."
Blazer is identified as the official that alerted the world governing body FIFA to allegations of bribery at a CFU meeting in Trinidad in May.
His disclosure led to Asian Football Confederation chief Mohamed Bin Hammam withdrawing from the FIFA presidential race, clearing the way for Sepp Blatter to win a fourth term.
Bin Hamman was also banned from football activities for life, and former CFU and CONCACAF president Jack Warner of Trinidad and Tobago resigned in disgrace.
Acting CONCACAF president Lisle Austin of Barbados attempted to sack Blazer for what he described as "unauthorised action".
CONCACAF's executive committee however, closed ranks and ousted Austin, indicating he also lacked the authority to fire Blazer.
FIFA then suspended Austin after he took CONCACAF to court in the Bahamas for locking him out of its corporate offices here.