The draw brings an end to Ronald Koeman's perfect start as Barcelona manager but he might not be too displeased with a point, even if his team also had chances to snatch a winner.
Both Lionel Messi and Barcelona appear keen to put on a united front, at least for now, ahead of their return to La Liga later this month.
A mess of a season could still be saved by the Champions League but even the most optimistic of fans expect the worst against Bayern Munich, Barcelona's probable opponents in the quarter-finals.
Antoine Griezmann picked up a "muscle injury in the quadriceps of his right leg" during Barcelona's 1-0 win over Real Valladolid in La Liga on Saturday.
Barcelona and Espanyol were both reduced to 10 men in the second half before Luis Suarez netted the winner for the home side at the Camp Nou.
Antoine Griezmann returned to Barcelona's starting line-up at La Ceramica and repaid the faith with a stunning goal, teed up by Lionel Messi.
Antoine Griezmann is ready to return to the field for Barcelona after a forced break due to coronavirus.
Antoine Griezmann scored for Barcelona as they secured a 1-1 draw against Napoli in the first leg of their Champions League last-16 tie.
A slick Antoine Griezmann strike set Barcelona on their way against Getafe in La Liga on Saturday before they survived a late onslaught from the gritty visitors to win 2-1.
Barcelona successfully bounced back from Saturday's surprise La Liga loss away at Valencia by hammering Leganes 5-0 in the Copa del Rey.
Valencia will provide Barcelona's new manager Quique Setien with his first true test and an opportunity to make his mark.
Five goals in a wild second half saw Atletico Madrid beat Barcelona 3-2 to seal a Super Cup final spot against Real Madrid.
A mistake by Barcelona's usually excellent goalkeeper Marc-Andre ter Stegen gifted Real Sociedad an equaliser in a thrilling La Liga contest.
Luis Suarez scored a goal with his backheel in a La Liga match against Mallorca and called it the "best goal of my career".
Trouble returned to Real Madrid after they endured their first La Liga defeat of the season at newly-promoted Real Mallorca.
France vs Turkey: Substitute Olivier Giroud put France ahead on 76 minutes but Kaan Ayhan nodded in an equaliser six minutes later.
La Liga: The Spanish Football Federation found FC Barcelona guilty of holding talks with Antoine Griezmann when he was still a Atletico Madrid player without their permission.
France cruised past Albania 4-1 on Saturday to move back to the top of their group in qualifying for Euro 2020.