Real Madrid were held to a 2-2 draw by Celta Vigo thanks to a late goal by Santi Mina.
Euro Qualifiers: Spain will need to beat Sweden in Solna on Tuesday to be sure of qualification with two games to spare.
Spain struggled to break down a determined Sweden defence at the Santiago Bernabeu until Sergio Ramos struck in the 64th minute
Spain beat a spirited Norway 2-1 in their opening Euro 2020 qualifier, while teenage striker Moise Kean netted in Italy's win over Finland.
Girona came from behind to pull off a shock 2-1 victory at the Santiago Bernabeu.
Eibar shoot up to seventh, a reward for their first ever victory over Real Madrid at the 11th attempt.
Spain needed 21-year-old debutant Brais Mendez, on as a substitute, to score the only goal of a scrappy game.
Paco Alcacer netted twice in the first half to make it eight goals in 14 Spain appearances.
Sergio Ramos has launched a scathing attack on Antoine Griezmann's attitude after the French forward said he is on a par with Lionel Messi and Cristiano Ronaldo.
Zinedine Zidane stated that the two stars played a good role in helping Real Madrid win the third consecutive title of the Champions League when he was the coach.
Jurgen Klopp said Loris Karius' errors in the Champions League final defeat to Real Madrid were because he was concussed.
Russia pulled off a major upset when they beat Spain on penalties in the FIFA World Cup 2018 Round of 16 match.
Host nation Russia beat Spain in a penalty shootout to move into the World Cup quarter-finals.
Spain face a tough challenge to reach the FIFA World Cup 2018 knockout as the 2010 champions take on eliminated Morocco in their Group B clash at Kaliningrad Stadium on Monday.
FIFA World Cup 2018, Highlights Football Match Score Portugal vs Spain: The match will be played at the Fisht Olympic Stadium in Sochi.
Spain and Portugal clash on Friday night in the first high-profile encounter of the World Cup in Russia.
Friday's World Cup clash between Portugal and Spain will be their fourth meeting at a major tournament this century.
The now-infamous incident during the Champions League final has put a big question mark of Mohamed Salahs World Cup participation.