Everton had come from 4-2 down to snatch a draw at Old Trafford last season, a result that played a key role in City eventually overhauling their rivals to win the title.
Having started their march to the last World Cup final with a win over Denmark, Holland will bid to begin their Euro 2012 campaign in identical fashion when the teams meet in Kharkiv on Saturday.
Even fully fit, the Netherlands defense was always going to be the team's soft spot at the European Championship. Struggling with injury makes it even worse.
England may appear to be in turmoil having only hired a coach a month ago and losing three key players to injury in the last 10 days but Johnny Heitinga believes all is not doom and gloom.