Former World Cup winner Sami Khedira has been ruled out of Wednesday's Champions League tie against Atletico Madrid.
Juventus open their campaign on Saturday against a sombre backdrop of a country in mourning following the Genoa bridge disaster.
Germany face another test of mettle after their historic Euro 2016 quarter-final win over Italy. However, the world champions are without three stars with defender Mats Hummels suspended, plus striker Mario Gomez and midfielder Sami Khedira injured
Germany have defender Mats Hummels suspended while Mario Gomez and Sami Khedira are out with injury. Gomez will miss the rest of the tournament
Mario Gomez is down with a
Germany could be without the services of Sami Khedira and Mario Gomez due to the injury while they Mats Hummels will miss the semi-final of Euro 2016 due to a one-match suspension
England's come-from-behind win over Germany will give them plenty of hope ahead of the Euro 2016 in France.
Sami Khedira went off injured after just nine minutes of the local Serie A derby against Torino, prompting fears he had torn a calf muscle.
Alvaro Morata, Sami Khedira and Paulo Dybala scored a goal each to help Juventus beat Bologna 3-1.
Injury-prone Sami Khedira was stretchered off during Juventus F.C. vs Marseille pre-season friendly on Saturday.
Sami Khedira will move to Italian champions Juventus at the end of the month when his Madrid contract expires after falling out of favour at the Spanish club last season.
Sami Khedira has signed a four-year contract with the Italian champions which expires on June 30, 2019.
After carrying out a secret medical in Madrid, Juventus expect to finalise a deal worth around four million euros a season in the next few days.
Germany midfielder Sami Khedira, who joined Real Madrid in 2010, has been linked to Bundesliga side Schalke 04.
Khedira has had an injury disrupted 18 months with the European champions after suffering a cruciate ligament injury whilst on international duty with Germany
Sami Khedira's current contract at the Champions League holders expires in the summer and clubs outside of Spain are free to offer him a deal from January 1.
Sami Khedira had collided with Cornella midfielder David Garcia shortly after halftime at Real Madrid's Bernabeu stadium and after playing on for a few minutes he was replaced by Jese.
Sami Khedira, a member of Germany's World Cup-winning side, faces renewed competition for a first-team place at Real Madrid following the arrivals of compatriot Toni Kroos and Colombia star James Rodriguez.