Roger Federer booked a round of 32 match with Serbian Filip Krajinovic who surprised three-time Grand Slam winner Stan Wawrinka.
Roger Federer, who has won their last five encounters, including the 2017 Indian Wells final, said an in-form Stan Wawrinka is an opponent to be wary of.
Nick Kyrgios out-lasted Wawrinka 7-5, 6-7 (3/7), 6-4 to book a meeting with John Isner for a place in the final.
Novak Djokovic defeated Jo-Wilfried Tsonga 6-3, 7-5, 6-4 in straight sets.
Novak Djokovic will be up against Spain's Roberto Bautista Agut in the semi-final.
Marin Cilic crashed out of the Japan Open in a shock 3-6, 6-4, 7-6 defeat to Germany's Jan-Lennard Struff in the first round.
Stan Wawrinka has been struggling to find his best form since returning to the ATP Tour after two operations on his left knee a year ago.
Andy Murray lost 5-7, 6-2, 4-6, 4-6 to Spain's Fernando Verdasco in US Open second round.
Former US Open champions Stan Wawrinka and Svetlana Kuznetsova received wildcards into the event on Tuesday along with two-time Australian Open winner Victoria Azarenka, tournament organisers announced.
A 45-minute rain interruption did little to stop the progress of Rafael Nadal on Thursday at the Toronto Masters as he defeated Stan Wawrinka 7-5, 7-6 (7/4) to reach the quarter-finals.
The three-time Grand champion Wawrinka, currently world No. 224, missed the later part of the last season due to a knee injury that required surgery.
Stanislas Wawrinka, the three-time Grand Slam champion had an obliging opponent in South Africa-born Norrie, who was given a wild card entry after rising to 79th in the rankings.
Novak Djokovic cruised through to the French Open second round in straight sets.
Stan Wawrinka has been plagued by a knee injury and arrived at Roland Garros having won just one match on clay in Geneva last week, his first event in three months.
The 32-year-old world number 12 sat out the second half of 2017 after a knee operation following a first-round exit at Wimbledon in June.
The three-time Grand Slam winner, who defeated Rafael Nadal to win the 2014 Australian Open, has slipped to nine in the world rankings and faces a battle to climb higher after his early round exit.
Swiss Stan Wawinka will undergo a knee surgery and will not be defending his US Open crown.