Maicon was hurt in Roma's victory over Sampdoria in the Serie A on Sept. 25 and will not recover in time for Brazil's matches against South Korea next Saturday in Seoul, and Zambia on October 15 in Beijing.
The 32-year-old has been recalled to the national squad after a two-year absence for the Selecao's friendlies against Australia on Sunday and Portugal three days later.
New City boss Manuel Pellegrini said at the weekend that Maicon was not part of his plans and the Brazilian did not take part in the pre-season tour of South Africa.
The 31-year-old has made just eight first-team appearances since his August 2012 move to City from Italian Serie A outfit Inter Milan, reports Xinhua.
Premier League champions Manchester City clinched the signing of Brazil right-back Maicon from Inter Milan for an undisclosed fee on Friday.
Inter Milan are set to cash in on the transfer of Brazilian defender Maicon to Manchester City, according to reports on Thursday.
Inter Milan full-back Maicon could be out for up to a month after being diagnosed with a muscle strain in his left thigh.
Maicon is celebrating his successful return to Brazil's line-up and is hoping his impressive performance against Ecuador will keep him in the team against Paraguay in the Copa America quarter-finals on Sunday.