Tottenham Hotspur were dumped out of the FA Cup in the fourth round beaten 2-1 by second-tier Leeds United on Sunday, after holders Chelsea scraped a 2-2 draw at local rivals Brentford of League One.
Spurs, currently fourth in the Premier League, join Aston Villa, Norwich City and Queens Park Rangers in being eliminated from the tournament by lower-league opposition this weekend.
Three-time English champions Leeds, who stunned Manchester United in the third round in 2010, took a 15th-minute lead when Luke Varney scampered down the inside-left channel before calmly beating goalkeeper Brad Friedel.
Ross McCormack made it 2-0 five minutes into the second half with a sweet left-foot shot following a lobbed pass from El-Hadji Diouf, before Spurs replied through a Clint Dempsey header in the 58th minute.
McCormack had a chance to seal it in the 72nd minute, only for Friedel to save, but the Elland Road side withstood Spurs' attempts to find an equaliser to take their place in round five.