Ireland made their Test debut last year, suffering a final day defeat by Pakistan in Dublin.
Virat Kohli returns to action as Team India skipper after a period of rest and recuperation.
Ireland are third in Pool B and well-placed for a quarter-final spot, although they still have to face South Africa, Zimbabwe, defending champions India and Pakistan.
Ireland's win against UAE was too close for comfort as they managed to scrape past their opposition total with only two wickets in hand. They earlier had upset two-time Cup champions the West Indies.
Live cricket score and ball-by-ball commentary from the 16th World Cup match between Ireland and United Arab Emirates at the Brisbane Cricket Ground (Woolloongabba), Brisbane on Wednesday.