French Open finalist David Ferrer lost his first-round match Tuesday at the Topshelf Open, a grass-court tournament held the week before Wimbledon.
A single service break in the second set was enough for Xavier Malisse of Belgium to beat defending champion and top-seeded Ferrer in straight sets, 7-6 (3), 6-3.
The 2011 champion Roberta Vinci had no such problems, brushing aside Kaia Kanepi 6-3, 6-3 in the first match on center court to reach the second round.
Second-seeded Stanislas Wawrinka was playing Steve Darcis later on Tuesday in the first round. Wawrinka was to play Igor Sijsling, but the Dutchman pulled out with a stomach problem.