Rafael Nadal is looking for his first title on any surface since last summer and will meet 57th-ranked Aljaz Bedene. On the other hand, Roger Federer will play his first match in more than two months.
Janko Tipsarevic's inclusion in the 20th edition of the Chennai Open will see 10 players from world's top 50 list.
Bernard Tomic blew one set lead to lose to Pablo Cuevas, while Vasek Pospisil beat Aljaz Bedene in straight sets.
Stanislas Wawrinka cruised into the ATP Chennai Open final with a 7-5, 6-3 win over fourth seed David Goffin. Slovenian qualifier Aljaz Bedene stunned Roberto Bautista-Agut 3-6, 6-3, 7-6.