Moussa Konate scored two first-half goals as 10-man Senegal handed Uruguay its first-ever Olympic defeat in a 2-0 win on Sunday.
Konate tapped in the rebound from Cheikhou Kouyate's saved header for an easy 10th-minute opener in front of 76,071 at Wembley Stadium.
Uruguay's defense was left flat-footed again on Konate's second in the 37th when five defenders watched him head home a corner seven minutes after defender Abdoulaye Ba was red carded for tripping up Luis Suarez.
Konate has scored three goals at London 2012 for Olympics debutante Senegal, which leads Group A with four points from two games. Two-time Olympic champion Uruguay has three points going into its last game.