Manchester United midfielder Shinji Kagawa has been ruled out of Japan's World Cup qualifier in Oman on November 14 due to a knee injury he suffered a week ago, the Japan Football Association said Tuesday.
Kagawa was not among the 18 Europe-based players who coach Alberto Zaccheroni planned to call up for his 23-man squad for the Oman game, the association said.
The 23-year-old summer signing was injured in Manchester United's 3-2 Champions League win over Braga on October 23.
He will miss the top-of-the-table Premiership game with Chelsea on Sunday as his club wanted him to be out for four weeks.
Among the 18 Europe-based players are regulars such as CSKA Moscow playmaker Keisuke Honda and Inter-Milan defender Yuto Nagatomo. They also included Southampton striker Tadanari Lee, who has not played for Japan since suffering an ankle injury in March.
In World Cup qualifying, Japan are leading Asian Group B with 10 points from three wins over Oman, Jordan and Iraq as well as one draw with Australia.